Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1186/s40635-020-00362-8 http://scihub22266oqcxt.onion/10.1186/s40635-020-00362-8 33284413!7719737!33284413     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Intensive+Care+Med+Exp 2020 ; 8 (1): 72 Nephropedia Template TP {{tp|p=33284413|t=2020. Endotoxemia and circulating bacteriome in severe COVID-19 patients |pdf=|usr=}}{{33284413}} gab.com Text Endotoxemia and circulating bacteriome in severe COVID-19 patients JO: Intensive Care Med Exp http://www.kidney.de/pget.php?&tw=1&pmid=33284413 #FOAvip BACKGROUND: When severe, COVID-19 shares many clinical features with bacterial sepsis. Yet, secondary bacterial infection is uncommon. However, as epithelium is injured and barrier function is lost, bacterial products entering the circulation might contribute to the pathophysiology of COVID-19. METHODS: We studied 19 adults, severely ill patients with COVID-19 infection, who were admitted to King Chulalongkorn Memorial Hospital, Bangkok, Thailand, between 13th March and 17th April 2020. Blood samples on days 1, 3, and 7 of enrollment were analyzed for endotoxin activity assay (EAA), (1 --> 3)-beta-D-glucan (BG), and 16S rRNA gene sequencing to determine the circulating bacteriome. RESULTS: Of the 19 patients, 13 were in intensive care and 10 patients received mechanical ventilation. We found 8 patients with high EAA (>/= 0.6) and about half of the patients had high serum BG levels which tended to be higher in later in the illness. Although only 1 patient had a positive blood culture, 18 of 19 patients were positive for 16S rRNA gene amplification. Proteobacteria was the most abundant phylum. The diversity of bacterial genera was decreased overtime. CONCLUSIONS: Bacterial DNA and toxins were discovered in virtually all severely ill COVID-19 pneumonia patients. This raises a previously unrecognized concern for significant contribution of bacterial products in the pathogenesis of this disease. Twit Text FOAVip Endotoxemia and circulating bacteriome in severe COVID-19 patients ????Intensive Care Med Exp http://www.kidney.de/pget.php?&tw=1&pmid=33284413 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33284413 #FOAvip English Wikipedia <ref>{{Cite pmid|33284413}}</ref> Endotoxemia and circulating bacteriome in severe COVID-19 patients #MMPMID33284413 Sirivongrangson P; Kulvichit W; Payungporn S; Pisitkun T; Chindamporn A; Peerapornratana S; Pisitkun P; Chitcharoen S; Sawaswong V; Worasilchai N; Kampunya S; Putcharoen O; Thawitsri T; Leelayuwatanakul N; Kongpolprom N; Phoophiboon V; Sriprasart T; Samransamruajkit R; Tungsanga S; Tiankanon K; Lumlertgul N; Leelahavanichkul A; Sriphojanart T; Tantawichien T; Thisyakorn U; Chirathaworn C; Praditpornsilpa K; Tungsanga K; Eiam-Ong S; Sitprija V; Kellum JA; Srisawat N Intensive Care Med Exp 2020[Dec]; 8 (1): 72 PMID33284413show ga BACKGROUND: When severe, COVID-19 shares many clinical features with bacterial sepsis. Yet, secondary bacterial infection is uncommon. However, as epithelium is injured and barrier function is lost, bacterial products entering the circulation might contribute to the pathophysiology of COVID-19. METHODS: We studied 19 adults, severely ill patients with COVID-19 infection, who were admitted to King Chulalongkorn Memorial Hospital, Bangkok, Thailand, between 13th March and 17th April 2020. Blood samples on days 1, 3, and 7 of enrollment were analyzed for endotoxin activity assay (EAA), (1 --> 3)-beta-D-glucan (BG), and 16S rRNA gene sequencing to determine the circulating bacteriome. RESULTS: Of the 19 patients, 13 were in intensive care and 10 patients received mechanical ventilation. We found 8 patients with high EAA (>/= 0.6) and about half of the patients had high serum BG levels which tended to be higher in later in the illness. Although only 1 patient had a positive blood culture, 18 of 19 patients were positive for 16S rRNA gene amplification. Proteobacteria was the most abundant phylum. The diversity of bacterial genera was decreased overtime. CONCLUSIONS: Bacterial DNA and toxins were discovered in virtually all severely ill COVID-19 pneumonia patients. This raises a previously unrecognized concern for significant contribution of bacterial products in the pathogenesis of this disease. äEndotoxemia and circulating bacteriome in severe COVID-19 patients (epmc).pdf DeepDyve Pubget Overpricing