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10.1001/jamapediatrics.2020.5086

http://scihub22266oqcxt.onion/10.1001/jamapediatrics.2020.5086
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33284345!7921895!33284345
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suck abstract from ncbi


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pmid33284345      JAMA+Pediatr 2021 ; 175 (3): 260-266
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  • Evaluation of Rooming-in Practice for Neonates Born to Mothers With Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Italy #MMPMID33284345
  • Ronchi A; Pietrasanta C; Zavattoni M; Saruggia M; Schena F; Sinelli MT; Agosti M; Tzialla C; Varsalone FF; Testa L; Ballerini C; Ferrari S; Mangili G; Ventura ML; Perniciaro S; Spada E; Lunghi G; Piralla A; Baldanti F; Mosca F; Pugni L
  • JAMA Pediatr 2021[Mar]; 175 (3): 260-266 PMID33284345show ga
  • IMPORTANCE: The management of mother-infant dyads during the ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic constitutes a major issue for neonatologists. In mothers with SARS-CoV-2 infection, current recommendations suggest either to separate the dyad or encourage protected rooming-in under appropriate precautions. No data are available regarding the risk of mother-to-infant transmission of SARS-CoV-2 during rooming-in. OBJECTIVE: To evaluate the risk of postnatal transmission of SARS-CoV-2 from infected mothers to their neonates following rooming-in and breastfeeding. DESIGN, SETTING, AND PARTICIPANTS: A prospective, multicenter study enrolling mother-infant dyads from March 19 to May 2, 2020, followed up for 20 days of life (range, 18-22 days), was performed. The study was conducted at 6 coronavirus disease 2019 maternity centers in Lombardy, Northern Italy. Participants included 62 neonates born to 61 mothers with SARS-CoV-2 infection who were eligible for rooming-in practice based on the clinical condition of the mother and infants whose results of nasopharyngeal swabs were negative at birth. EXPOSURES: Mothers with SARS-CoV-2 infection were encouraged to practice rooming-in and breastfeeding under a standardized protocol to minimize the risk of viral transmission. MAIN OUTCOMES AND MEASURES: Clinical characteristics and real-time reverse transcriptase-polymerase chain reaction for SARS-CoV-2 on neonatal nasopharyngeal swabs at 0, 7, and 20 days of life. RESULTS: Of the 62 neonates enrolled (25 boys), born to 61 mothers (median age, 32 years; interquartile range, 28-36 years), only 1 infant (1.6%; 95% CI, 0%-8.7%) was diagnosed as having SARS-CoV-2 infection at postbirth checks. In that case, rooming-in was interrupted on day 5 of life because of severe worsening of the mother's clinical condition. The neonate became positive for the virus on day 7 of life and developed transient mild dyspnea. Ninety-five percent of the neonates enrolled were breastfed. CONCLUSIONS AND RELEVANCE: The findings of this cohort study provide evidence-based information on the management of mother-infant dyads in case of SARS-CoV-2 maternal infection suggesting that rooming-in and breastfeeding can be practiced in women who are able to care for their infants.
  • |*Pandemics[MESH]
  • |Adult[MESH]
  • |COVID-19/*epidemiology/transmission[MESH]
  • |Female[MESH]
  • |Follow-Up Studies[MESH]
  • |Humans[MESH]
  • |Infant, Newborn[MESH]
  • |Infectious Disease Transmission, Vertical/*prevention & control[MESH]
  • |Italy/epidemiology[MESH]
  • |Male[MESH]
  • |Mothers/*statistics & numerical data[MESH]
  • |Pregnancy[MESH]
  • |Pregnancy Complications, Infectious/*enzymology/epidemiology[MESH]
  • |Prospective Studies[MESH]


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