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10.1093/labmed/lmaa104

http://scihub22266oqcxt.onion/10.1093/labmed/lmaa104
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suck abstract from ncbi


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pmid33283230      Lab+Med 2021 ; 52 (2): e46-e49
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  • Potential Use of Antigen-Based Rapid Test for SARS-CoV-2 in Respiratory Specimens in Low-Resource Settings in Egypt for Symptomatic Patients and High-Risk Contacts #MMPMID33283230
  • Abdelrazik AM; Elshafie SM; Abdelaziz HM
  • Lab Med 2021[Mar]; 52 (2): e46-e49 PMID33283230show ga
  • OBJECTIVE: Because of the rapidly emerging SARS-CoV-2 pandemic and its wide public health challenges, rapid diagnosis is essential to decrease the spread. Antigen-based rapid detection tests are available; however, insufficient data about their performance are available. METHODS: The lateral-flow immunochromatographic BIOCREDIT COVID-19 antigen test was evaluated using nasopharyngeal swabs in a viral transport medium from patients with confirmed infection, contacts, and exposed healthcare professionals at Fayoum University Hospital in Egypt. Test performance was determined in comparison to the SARS-CoV-2 real-time reverse-transcription polymerase chain reaction (RT-PCR) test. RESULTS: Three hundred ten specimens from 3 categories-patients with confirmed diagnoses of COVID-19, contacts, and exposed healthcare professionals-were included; 188 specimens were RT-PCR-positive, from which 81 were detected by rapid antigen test. Overall sensitivity was 43.1%. Sensitivity was significantly higher in specimens with high viral loads. CONCLUSION: Poor sensitivity of the BIOCREDIT COVID-19 test does not permit its use for diagnosis, and it can only be used in conjunction with RT-PCR for screening.
  • |*COVID-19 Serological Testing[MESH]
  • |Adult[MESH]
  • |COVID-19/*diagnosis[MESH]
  • |Egypt[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Immunoassay/*statistics & numerical data[MESH]


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