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suck abstract from ncbi


10.1016/j.bbrc.2020.10.094

http://scihub22266oqcxt.onion/10.1016/j.bbrc.2020.10.094
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33272566!7678433!33272566
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suck abstract from ncbi

pmid33272566      Biochem+Biophys+Res+Commun 2021 ; 538 (?): 137-144
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  • Identifying and repurposing antiviral drugs against severe acute respiratory syndrome coronavirus 2 with in silico and in vitro approaches #MMPMID33272566
  • Watashi K
  • Biochem Biophys Res Commun 2021[Jan]; 538 (?): 137-144 PMID33272566show ga
  • Coronavirus infectious diseases 2019 (COVID-19), a global pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been a serious public health threat worldwide. So far, there are no drugs and vaccines whose efficacy has been well-proven. After the outbreak, there has been a massive search for anti-SARS-CoV-2 medications, focusing on approved drugs because repurposing approved drugs will take less time to reach clinical usage than new drugs. This article summarizes the studies using in silico and in vitro approaches to identify therapeutic candidates among approved drugs that target the SARS-CoV-2 life cycle.
  • |*COVID-19 Drug Treatment[MESH]
  • |Animals[MESH]
  • |Antiviral Agents/*chemistry/pharmacology/therapeutic use[MESH]
  • |Caco-2 Cells[MESH]
  • |Chlorocebus aethiops[MESH]
  • |Computer Simulation[MESH]
  • |Drug Repositioning/*methods[MESH]
  • |Humans[MESH]
  • |Mice[MESH]
  • |SARS-CoV-2/*drug effects[MESH]


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