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10.1093/rheumatology/keaa855 http://scihub22266oqcxt.onion/10.1093/rheumatology/keaa855 33271595!7798585!33271595     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33271595&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Rheumatology+(Oxford) 2021 ; 60 (4): 1902-1909 Nephropedia Template TP {{tp|p=33271595|t=2021. Risk of death among people with rare autoimmune diseases compared with the general population in England during the 2020 COVID-19 pandemic |pdf=|usr=}}{{33271595}} gab.com Text Risk of death among people with rare autoimmune diseases compared with the general population in England during the 2020 COVID-19 pandemic JO: Rheumatology (Oxford) http://www.kidney.de/pget.php?&tw=1&pmid=33271595 #FOAvip OBJECTIVES: To quantify the risk of death among people with rare autoimmune rheumatic diseases (RAIRD) during the UK 2020 COVID-19 pandemic compared with the general population, and compared with their pre-COVID risk. METHODS: We conducted a cohort study in Hospital Episode Statistics for England from 2003 onwards, and linked data from the NHS Personal Demographics Service. We used ONS published data for general population mortality rates. RESULTS: We included 168 691 people with a recorded diagnosis of RAIRD alive on 1 March 2020. Their median age was 61.7 (IQR 41.5-75.4) years, and 118 379 (70.2%) were female. Our case ascertainment methods had a positive predictive value of 85%. A total of 1815 (1.1%) participants died during March and April 2020. The age-standardized mortality rate (ASMR) among people with RAIRD (3669.3; 95% CI: 3500.4, 3838.1 per 100 000 person-years) was 1.44 (95% CI: 1.42, 1.45) times higher than the average ASMR during the same months of the previous 5 years, whereas in the general population of England it was 1.38 times higher. Age-specific mortality rates in people with RAIRD compared with the pre-COVID rates were higher from the age of 35 upwards, whereas in the general population the increased risk began from age 55 upwards. Women had a greater increase in mortality rates during COVID-19 compared with men. CONCLUSION: The risk of all-cause death is more prominently raised during COVID-19 among people with RAIRD than among the general population. We urgently need to quantify how much risk is due to COVID-19 infection and how much is due to disruption to health-care services. Twit Text FOAVip Risk of death among people with rare autoimmune diseases compared with the general population in England during the 2020 COVID-19 pandemic ????Rheumatology (Oxford) http://www.kidney.de/pget.php?&tw=1&pmid=33271595 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33271595 #FOAvip English Wikipedia <ref>{{Cite pmid|33271595}}</ref> Risk of death among people with rare autoimmune diseases compared with the general population in England during the 2020 COVID-19 pandemic #MMPMID33271595 Peach E; Rutter M; Lanyon P; Grainge MJ; Hubbard R; Aston J; Bythell M; Stevens S; Pearce F Rheumatology (Oxford) 2021[Apr]; 60 (4): 1902-1909 PMID33271595show ga OBJECTIVES: To quantify the risk of death among people with rare autoimmune rheumatic diseases (RAIRD) during the UK 2020 COVID-19 pandemic compared with the general population, and compared with their pre-COVID risk. METHODS: We conducted a cohort study in Hospital Episode Statistics for England from 2003 onwards, and linked data from the NHS Personal Demographics Service. We used ONS published data for general population mortality rates. RESULTS: We included 168 691 people with a recorded diagnosis of RAIRD alive on 1 March 2020. Their median age was 61.7 (IQR 41.5-75.4) years, and 118 379 (70.2%) were female. Our case ascertainment methods had a positive predictive value of 85%. A total of 1815 (1.1%) participants died during March and April 2020. The age-standardized mortality rate (ASMR) among people with RAIRD (3669.3; 95% CI: 3500.4, 3838.1 per 100 000 person-years) was 1.44 (95% CI: 1.42, 1.45) times higher than the average ASMR during the same months of the previous 5 years, whereas in the general population of England it was 1.38 times higher. Age-specific mortality rates in people with RAIRD compared with the pre-COVID rates were higher from the age of 35 upwards, whereas in the general population the increased risk began from age 55 upwards. Women had a greater increase in mortality rates during COVID-19 compared with men. CONCLUSION: The risk of all-cause death is more prominently raised during COVID-19 among people with RAIRD than among the general population. We urgently need to quantify how much risk is due to COVID-19 infection and how much is due to disruption to health-care services. |*Autoimmune Diseases/classification/diagnosis/mortality[MESH] |COVID-19/*mortality/therapy[MESH] |Cause of Death[MESH] |Cohort Studies[MESH] |England/epidemiology[MESH] |Female[MESH] |Humans[MESH] |Male[MESH] |Middle Aged[MESH] |Mortality[MESH] |Needs Assessment[MESH] |Prognosis[MESH] |Risk Assessment/methods/statistics & numerical data[MESH] |Risk Factors[MESH] |SARS-CoV-2/isolation & purification[MESH] |Sex Factors[MESH]Risk of death among people with rare autoimmune diseases compared with(epmc).pdf DeepDyve Pubget Overpricing