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10.1016/j.medcle.2020.08.001 http://scihub22266oqcxt.onion/10.1016/j.medcle.2020.08.001 33263084!7691846!33263084     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Med+Clin+(Engl+Ed) 2021 ; 156 (1): 7-12 Nephropedia Template TP {{tp|p=33263084|t=2021. Association between high-dose steroid therapy, respiratory function, and time to discharge in patients with COVID-19: Cohort study |pdf=|usr=}}{{33263084}} gab.com Text Association between high-dose steroid therapy, respiratory function, and time to discharge in patients with COVID-19: Cohort study JO: Med Clin (Engl Ed) http://www.kidney.de/pget.php?&tw=1&pmid=33263084 #FOAvip OBJECTIVE: To analyze whether there is an association between the use glucocorticoids at high doses, and the evolution of saturation/fraction of inspired oxygen (SAFI) or time to discharge, in patients hospitalized with COVID-19. METHODS: This was an observational study on a cohort of 418 patients admitted to three regional hospitals in Catalonia, Spain. As primary outcomes, we studied the evolution of SAFI in the first 48?h of treatment and the time to discharge. The results were compared between patients treated and untreated with glucocorticoids (methylprednisolone 1?mg/kg/day o dexamethasone 20-40?mg/day) through sub-cohort analyses matched for multiple clinical and prognostic factors, as well as through Cox multivariate models adjusted for prognostic factors. The simultaneous use of different treatments for COVID-19 was taken into account, both in sub-cohorts matching and in COX regression. RESULTS: There were 187 patients treated with glucocorticoids; of these, 25 patients could be matched with an equivalent number of control patients. In the analysis of these matched sub-cohorts, no significant difference was observed in time to discharge (log-rank: p?=?0.291) or the increment in SAFI at 48?h of treatment (glucocorticoides: -0.04; controls: +0.37; p?=?0.095). Multivariate models using Cox regression showed a significantly longer time to discharge in patients treated with glucocorticoids (hazard ratio: 7.26; 95% IC: 3.30-15.95). CONCLUSIONS: We have not found improvement in respiratory function or time until discharge, associated with the use of glucocorticoids at high doses. Twit Text FOAVip Association between high-dose steroid therapy, respiratory function, and time to discharge in patients with COVID-19: Cohort study ????Med Clin (Engl Ed) http://www.kidney.de/pget.php?&tw=1&pmid=33263084 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33263084 #FOAvip English Wikipedia <ref>{{Cite pmid|33263084}}</ref> Association between high-dose steroid therapy, respiratory function, and time to discharge in patients with COVID-19: Cohort study #MMPMID33263084 Rodriguez-Molinero A; Perez-Lopez C; Galvez-Barron C; Minarro A; Rodriguez Gullello EA; Collado Perez I; Mila Rafols N; Monaco EE; Hidalgo Garcia A; Ananos Carrasco G; Chamero Pastilla A Med Clin (Engl Ed) 2021[Jan]; 156 (1): 7-12 PMID33263084show ga OBJECTIVE: To analyze whether there is an association between the use glucocorticoids at high doses, and the evolution of saturation/fraction of inspired oxygen (SAFI) or time to discharge, in patients hospitalized with COVID-19. METHODS: This was an observational study on a cohort of 418 patients admitted to three regional hospitals in Catalonia, Spain. As primary outcomes, we studied the evolution of SAFI in the first 48?h of treatment and the time to discharge. The results were compared between patients treated and untreated with glucocorticoids (methylprednisolone 1?mg/kg/day o dexamethasone 20-40?mg/day) through sub-cohort analyses matched for multiple clinical and prognostic factors, as well as through Cox multivariate models adjusted for prognostic factors. The simultaneous use of different treatments for COVID-19 was taken into account, both in sub-cohorts matching and in COX regression. RESULTS: There were 187 patients treated with glucocorticoids; of these, 25 patients could be matched with an equivalent number of control patients. In the analysis of these matched sub-cohorts, no significant difference was observed in time to discharge (log-rank: p?=?0.291) or the increment in SAFI at 48?h of treatment (glucocorticoides: -0.04; controls: +0.37; p?=?0.095). Multivariate models using Cox regression showed a significantly longer time to discharge in patients treated with glucocorticoids (hazard ratio: 7.26; 95% IC: 3.30-15.95). CONCLUSIONS: We have not found improvement in respiratory function or time until discharge, associated with the use of glucocorticoids at high doses. äAssociation between high-dose steroid therapy, respiratory function, a(epmc).pdf DeepDyve Pubget Overpricing