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10.3892/etm.2020.9456 http://scihub22266oqcxt.onion/10.3892/etm.2020.9456 33262810!7690237!33262810     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Exp+Ther+Med 2021 ; 21 (1): 24 Nephropedia Template TP {{tp|p=33262810|t=2021. Interleukin-6 signaling blockade treatment for cytokine release syndrome in COVID-19 (Review) |pdf=|usr=}}{{33262810}} gab.com Text Interleukin-6 signaling blockade treatment for cytokine release syndrome in COVID-19 (Review) JO: Exp Ther Med http://www.kidney.de/pget.php?&tw=1&pmid=33262810 #FOAvip A severe immune response in patients with coronavirus disease 2019 (COVID-19) can cause a potentially lethal unconstrained inflammatory cytokine storm, known as cytokine release syndrome (CRS). The present study provides an overview of the biology underlying CRS and how targeted inhibition of interleukin (IL)-6 signaling may improve outcomes and the survival of patients suffering from COVID-19. Preliminary clinical results have indicated that antagonism of the IL-6 receptor (IL-6R), including with the FDA-approved humanized monoclonal antibody tocilizumab, can improve the outcomes of patients with severe or critical COVID-19 while maintaining a good safety profile. The available clinical data support the expansion of clinical trials using IL-6R targeting inhibitors for severe and critical COVID-19 treatment. Twit Text FOAVip Interleukin-6 signaling blockade treatment for cytokine release syndrome in COVID-19 (Review) ????Exp Ther Med http://www.kidney.de/pget.php?&tw=1&pmid=33262810 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33262810 #FOAvip English Wikipedia <ref>{{Cite pmid|33262810}}</ref> Interleukin-6 signaling blockade treatment for cytokine release syndrome in COVID-19 (Review) #MMPMID33262810 Chen JJ; Zhang LN; Hou H; Xu L; Ji K Exp Ther Med 2021[Jan]; 21 (1): 24 PMID33262810show ga A severe immune response in patients with coronavirus disease 2019 (COVID-19) can cause a potentially lethal unconstrained inflammatory cytokine storm, known as cytokine release syndrome (CRS). The present study provides an overview of the biology underlying CRS and how targeted inhibition of interleukin (IL)-6 signaling may improve outcomes and the survival of patients suffering from COVID-19. Preliminary clinical results have indicated that antagonism of the IL-6 receptor (IL-6R), including with the FDA-approved humanized monoclonal antibody tocilizumab, can improve the outcomes of patients with severe or critical COVID-19 while maintaining a good safety profile. The available clinical data support the expansion of clinical trials using IL-6R targeting inhibitors for severe and critical COVID-19 treatment. äInterleukin-6 signaling blockade treatment for cytokine release syndro(epmc).pdf DeepDyve Pubget Overpricing