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10.1186/s40478-020-01077-3 http://scihub22266oqcxt.onion/10.1186/s40478-020-01077-3 33261657!7706050!33261657     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Acta+Neuropathol+Commun 2020 ; 8 (1): 209 Nephropedia Template TP {{tp|p=33261657|t=2020. Cerebral organoids: emerging ex vivo humanoid models of glioblastoma |pdf=|usr=}}{{33261657}} gab.com Text Cerebral organoids: emerging ex vivo humanoid models of glioblastoma JO: Acta Neuropathol Commun http://www.kidney.de/pget.php?&tw=1&pmid=33261657 #FOAvip Glioblastoma is an aggressive form of brain cancer that has seen only marginal improvements in its bleak survival outlook of 12-15 months over the last forty years. There is therefore an urgent need for the development of advanced drug screening platforms and systems that can better recapitulate glioblastoma's infiltrative biology, a process largely responsible for its relentless propensity for recurrence and progression. Recent advances in stem cell biology have allowed the generation of artificial tridimensional brain-like tissue termed cerebral organoids. In addition to their potential to model brain development, these reagents are providing much needed synthetic humanoid scaffolds to model glioblastoma's infiltrative capacity in a faithful and scalable manner. Here, we highlight and review the early breakthroughs in this growing field and discuss its potential future role for glioblastoma research. Twit Text FOAVip Cerebral organoids: emerging ex vivo humanoid models of glioblastoma ????Acta Neuropathol Commun http://www.kidney.de/pget.php?&tw=1&pmid=33261657 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33261657 #FOAvip English Wikipedia <ref>{{Cite pmid|33261657}}</ref> Cerebral organoids: emerging ex vivo humanoid models of glioblastoma #MMPMID33261657 Papaioannou MD; Sangster K; Sajid RS; Djuric U; Diamandis P Acta Neuropathol Commun 2020[Dec]; 8 (1): 209 PMID33261657show ga Glioblastoma is an aggressive form of brain cancer that has seen only marginal improvements in its bleak survival outlook of 12-15 months over the last forty years. There is therefore an urgent need for the development of advanced drug screening platforms and systems that can better recapitulate glioblastoma's infiltrative biology, a process largely responsible for its relentless propensity for recurrence and progression. Recent advances in stem cell biology have allowed the generation of artificial tridimensional brain-like tissue termed cerebral organoids. In addition to their potential to model brain development, these reagents are providing much needed synthetic humanoid scaffolds to model glioblastoma's infiltrative capacity in a faithful and scalable manner. Here, we highlight and review the early breakthroughs in this growing field and discuss its potential future role for glioblastoma research. |*Brain Neoplasms[MESH] |*Glioblastoma[MESH] |*Organoids[MESH] |Biomedical Research[MESH] |Cerebrum[MESH] |Humans[MESH] |Models, Neurological[MESH]Cerebral organoids: emerging ex vivo humanoid models of glioblastoma (epmc).pdf DeepDyve Pubget Overpricing