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10.1016/j.jcrc.2020.11.012

http://scihub22266oqcxt.onion/10.1016/j.jcrc.2020.11.012
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33260010!7680030!33260010
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suck abstract from ncbi


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pmid33260010      J+Crit+Care 2021 ; 62 (ä): 46-48
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  • COVID-19 and non-COVID ARDS patients demonstrate a distinct response to low dose steroids- A retrospective observational study #MMPMID33260010
  • Longobardo A; Snow TAC; Montanari C; Shulman R; Singer M; Arulkumaran N
  • J Crit Care 2021[Apr]; 62 (ä): 46-48 PMID33260010show ga
  • Patients with COVID-19 ARDS have distinct physiological and immunological phenotypes compared to patients with non-COVID ARDS. Patients with COVID-19 ARDS (n = 32) had a significant improvement in PaO(2): FiO(2) ratio (p = 0.046) following low-dose steroid treatment, unlike patients with non-COVID ARDS (n = 16) (p = 0.529). Patients with COVID-19 ARDS had a greater fall in CRP compared to patients with non-COVID ARDS, albeit not statistically significant (p = 0.07). Our novel findings highlight differences in the underlying physiological and immunological phenotypes between COVID-19 and non-COVID ARDS, with implications for future ARDS studies.
  • |*COVID-19 Drug Treatment[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Anti-Inflammatory Agents/*therapeutic use[MESH]
  • |C-Reactive Protein/drug effects[MESH]
  • |COVID-19/*physiopathology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Hydrocortisone/therapeutic use[MESH]
  • |London/epidemiology[MESH]
  • |Male[MESH]
  • |Methylprednisolone/therapeutic use[MESH]
  • |Middle Aged[MESH]
  • |Phenotype[MESH]
  • |Respiratory Distress Syndrome/*drug therapy/*physiopathology[MESH]
  • |Respiratory Mechanics[MESH]
  • |Retrospective Studies[MESH]
  • |SARS-CoV-2[MESH]


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