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10.1017/S0950268820002939

http://scihub22266oqcxt.onion/10.1017/S0950268820002939
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33256863!7737118!33256863
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suck abstract from ncbi


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pmid33256863      Epidemiol+Infect 2020 ; 148 (ä): e292
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  • High MERS-CoV seropositivity associated with camel herd profile, husbandry practices and household socio-demographic characteristics in Northern Kenya #MMPMID33256863
  • Ngere I; Munyua P; Harcourt J; Hunsperger E; Thornburg N; Muturi M; Osoro E; Gachohi J; Bodha B; Okotu B; Oyugi J; Jaoko W; Mwatondo A; Njenga K; Widdowson MA
  • Epidemiol Infect 2020[Dec]; 148 (ä): e292 PMID33256863show ga
  • Despite high exposure to Middle East respiratory syndrome coronavirus (MERS-CoV), the predictors for seropositivity in the context of husbandry practices for camels in Eastern Africa are not well understood. We conducted a cross-sectional survey to describe the camel herd profile and determine the factors associated with MERS-CoV seropositivity in Northern Kenya. We enrolled 29 camel-owning households and administered questionnaires to collect herd and household data. Serum samples collected from 493 randomly selected camels were tested for anti-MERS-CoV antibodies using a microneutralisation assay, and regression analysis used to correlate herd and household characteristics with camel seropositivity. Households reared camels (median = 23 camels and IQR 16-56), and at least one other livestock species in two distinct herds; a home herd kept near homesteads, and a range/fora herd that resided far from the homestead. The overall MERS-CoV IgG seropositivity was 76.3%, with no statistically significant difference between home and fora herds. Significant predictors for seropositivity (P ? 0.05) included camels 6-10 years old (aOR 2.3, 95% CI 1.0-5.2), herds with ?25 camels (aOR 2.0, 95% CI 1.2-3.4) and camels from Gabra community (aOR 2.3, 95% CI 1.2-4.2). These results suggest high levels of virus transmission among camels, with potential for human infection.
  • |*Camelus[MESH]
  • |*Middle East Respiratory Syndrome Coronavirus/immunology[MESH]
  • |Adult[MESH]
  • |Age Factors[MESH]
  • |Animal Husbandry/*methods[MESH]
  • |Animals[MESH]
  • |Antibodies, Neutralizing/blood[MESH]
  • |Antibodies, Viral/blood[MESH]
  • |Coronavirus Infections/*epidemiology/transmission[MESH]
  • |Cross-Sectional Studies[MESH]
  • |Educational Status[MESH]
  • |Family Characteristics[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Kenya/epidemiology[MESH]
  • |Male[MESH]
  • |Regression Analysis[MESH]
  • |Seroepidemiologic Studies[MESH]
  • |Socioeconomic Factors[MESH]
  • |Surveys and Questionnaires[MESH]
  • |Transients and Migrants[MESH]


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