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10.3390/ijms21238903

http://scihub22266oqcxt.onion/10.3390/ijms21238903
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33255339!7727649!33255339
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suck abstract from ncbi


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pmid33255339      Int+J+Mol+Sci 2020 ; 21 (23): ä
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  • A Cell for the Ages: Human gammadelta T Cells across the Lifespan #MMPMID33255339
  • Clark BL; Thomas PG
  • Int J Mol Sci 2020[Nov]; 21 (23): ä PMID33255339show ga
  • The complexity of the human immune system is exacerbated by age-related changes to immune cell functionality. Many of these age-related effects remain undescribed or driven by mechanisms that are poorly understood. gammadelta T cells, while considered an adaptive subset based on immunological ontogeny, retain both innate-like and adaptive-like characteristics. This T cell population is small but mighty, and has been implicated in both homeostatic and disease-induced immunity within tissues and throughout the periphery. In this review, we outline what is known about the effect of age on human peripheral gammadelta T cells, and call attention to areas of the field where further research is needed.
  • |Aging/*immunology[MESH]
  • |Humans[MESH]
  • |Immunity, Innate/*immunology[MESH]
  • |Longevity/immunology[MESH]
  • |Receptors, Antigen, T-Cell, gamma-delta/*immunology[MESH]


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