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10.1016/j.mehy.2020.110177 http://scihub22266oqcxt.onion/10.1016/j.mehy.2020.110177 33254499!7417258!33254499     free     free     free Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 249.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Med+Hypotheses 2020 ; 144 (ä): 110177 Nephropedia Template TP {{tp|p=33254499|t=2020. COVID-19: Electrophysiological mechanisms underlying sudden cardiac death during exercise with facemasks |pdf=|usr=}}{{33254499}} gab.com Text COVID-19: Electrophysiological mechanisms underlying sudden cardiac death during exercise with facemasks JO: Med Hypotheses http://www.kidney.de/pget.php?&tw=1&pmid=33254499 #FOAvip The mandatory use of facemasks is a public health measure implemented by various countries in response to the novel coronavirus disease 19 (COVID-19) pandemic. However, there have been case reports of sudden cardiac death (SCD) with the wearing of facemasks during exercise. In this paper, we hypothesize that exercise with facemasks may increase the risk of ventricular tachycardia/ventricular fibrillation (VT/VF) leading to SCD via the development of acute and/or intermittent hypoxia and hypercapnia. We discuss the potential underlying mechanisms including increases in adrenergic stimulation and oxidative stress leading to electrophysiological abnormalities that promote arrhythmias via non-reentrant and reentrant mechanisms. Given the interplay of multiple variables contributing to the increased arrhythmic risk, we advise avoidance of a facemask during high intensity exercise, or if wearing of a mask is mandatory, exercise intensity should remain low to avoid precipitation of lethal arrhythmias. However, we cannot exclude the possibility of an arrhythmic substrate even with low intensity exercise especially in those with established chronic cardiovascular disease in whom baseline electrophysiological abnormalities may be found. Twit Text FOAVip COVID-19: Electrophysiological mechanisms underlying sudden cardiac death during exercise with facemasks ????Med Hypotheses http://www.kidney.de/pget.php?&tw=1&pmid=33254499 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33254499 #FOAvip English Wikipedia <ref>{{Cite pmid|33254499}}</ref> COVID-19: Electrophysiological mechanisms underlying sudden cardiac death during exercise with facemasks #MMPMID33254499 Lee S; Li G; Liu T; Tse G Med Hypotheses 2020[Nov]; 144 (ä): 110177 PMID33254499show ga The mandatory use of facemasks is a public health measure implemented by various countries in response to the novel coronavirus disease 19 (COVID-19) pandemic. However, there have been case reports of sudden cardiac death (SCD) with the wearing of facemasks during exercise. In this paper, we hypothesize that exercise with facemasks may increase the risk of ventricular tachycardia/ventricular fibrillation (VT/VF) leading to SCD via the development of acute and/or intermittent hypoxia and hypercapnia. We discuss the potential underlying mechanisms including increases in adrenergic stimulation and oxidative stress leading to electrophysiological abnormalities that promote arrhythmias via non-reentrant and reentrant mechanisms. Given the interplay of multiple variables contributing to the increased arrhythmic risk, we advise avoidance of a facemask during high intensity exercise, or if wearing of a mask is mandatory, exercise intensity should remain low to avoid precipitation of lethal arrhythmias. However, we cannot exclude the possibility of an arrhythmic substrate even with low intensity exercise especially in those with established chronic cardiovascular disease in whom baseline electrophysiological abnormalities may be found. |*Death, Sudden, Cardiac[MESH] |*Electrophysiological Phenomena[MESH] |*Exercise[MESH] |*Masks[MESH] |Arrhythmias, Cardiac/physiopathology[MESH] |COVID-19/*complications/*mortality/physiopathology[MESH] |Electrocardiography[MESH] |Humans[MESH] |Hypercapnia[MESH] |Hypoxia[MESH] |Models, Theoretical[MESH] |Oxidative Stress[MESH] |Reactive Oxygen Species/metabolism[MESH] |Risk[MESH] |Tachycardia, Ventricular/physiopathology[MESH]COVID-19: Electrophysiological mechanisms underlying sudden cardiac de(epmc).pdf DeepDyve Pubget Overpricing