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10.1093/bib/bbaa330

http://scihub22266oqcxt.onion/10.1093/bib/bbaa330
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suck abstract from ncbi


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pmid33253353      Brief+Bioinform 2021 ; 22 (2): 1508-1510
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  • Drug repurposing for COVID-19: could vitamin C combined with glycyrrhizic acid be at play by the findings of Li et al s database-based network pharmacology analysis? #MMPMID33253353
  • Huang YX; Wang WX; Tang YP; Yue SJ
  • Brief Bioinform 2021[Mar]; 22 (2): 1508-1510 PMID33253353show ga
  • The outbreak and pandemic of SARS-CoV-2 in 2019 has caused a severe public health burden and will challenge global health for the future. The discovery and mechanistic investigation of drugs against Coronavirus disease 2019 (COVID-19) is in deadly demand. The paper published by Li and colleagues proposed the hypothesis that vitamin C combined with glycyrrhizic acid in treating COVID-19 and its mechanistic investigation was performed by a database-based network pharmacology. In this letter, we present critical comments on the limitations and insufficiencies involved, from both the perspective of network pharmacology and current evidence on COVID-19.
  • |*COVID-19 Drug Treatment[MESH]
  • |*Databases, Pharmaceutical[MESH]
  • |*Drug Repositioning[MESH]
  • |Ascorbic Acid/administration & dosage/*therapeutic use[MESH]
  • |COVID-19/virology[MESH]
  • |Glycyrrhizic Acid/administration & dosage/*therapeutic use[MESH]
  • |Humans[MESH]


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