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10.2217/nnm-2020-0269 http://scihub22266oqcxt.onion/10.2217/nnm-2020-0269 33252301!ä!33252301 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nanomedicine+(Lond) 2020 ; 15 (29): 2883-2894 Nephropedia Template TP {{tp|p=33252301|t=2020. Nanomedicinal delivery of stimulator of interferon genes agonists: recent advances in virus vaccination |pdf=|usr=}}{{33252301}} gab.com Text Nanomedicinal delivery of stimulator of interferon genes agonists: recent advances in virus vaccination JO: Nanomedicine (Lond) http://www.kidney.de/pget.php?&tw=1&pmid=33252301 #FOAvip The discovery of stimulator of interferon genes (STING) and their agonists as primary components that link antiviral innate and adaptive immunity has motivated growing research on STING agonist-mediated immunotherapy and vaccine development. To overcome the delivery challenge in shuttling highly polar STING agonists, typically in the form of cyclic dinucleotides, to target cells and to STING proteins in cellular cytosol, numerous nanoformulation strategies have been implemented for effective STING activation. While many STING-activating nanoparticles are developed to enhance anticancer immunotherapy, their adoption as vaccine adjuvant has vastly propelled antiviral vaccination efforts against challenging public health threats, including HIV, influenza and coronaviruses. In light of the COVID-19 pandemic that has thrusted vaccine development into the public spotlight, this review highlights advances in nanomedicinal STING agonist delivery with an emphasis on their applications in antiviral vaccination. Twit Text FOAVip Nanomedicinal delivery of stimulator of interferon genes agonists: recent advances in virus vaccination ????Nanomedicine (Lond) http://www.kidney.de/pget.php?&tw=1&pmid=33252301 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33252301 #FOAvip English Wikipedia <ref>{{Cite pmid|33252301}}</ref> Nanomedicinal delivery of stimulator of interferon genes agonists: recent advances in virus vaccination #MMPMID33252301 Chattopadhyay S; Hu CJ Nanomedicine (Lond) 2020[Dec]; 15 (29): 2883-2894 PMID33252301show ga The discovery of stimulator of interferon genes (STING) and their agonists as primary components that link antiviral innate and adaptive immunity has motivated growing research on STING agonist-mediated immunotherapy and vaccine development. To overcome the delivery challenge in shuttling highly polar STING agonists, typically in the form of cyclic dinucleotides, to target cells and to STING proteins in cellular cytosol, numerous nanoformulation strategies have been implemented for effective STING activation. While many STING-activating nanoparticles are developed to enhance anticancer immunotherapy, their adoption as vaccine adjuvant has vastly propelled antiviral vaccination efforts against challenging public health threats, including HIV, influenza and coronaviruses. In light of the COVID-19 pandemic that has thrusted vaccine development into the public spotlight, this review highlights advances in nanomedicinal STING agonist delivery with an emphasis on their applications in antiviral vaccination. |*COVID-19 Drug Treatment[MESH] |*Pandemics[MESH] |Antiviral Agents/therapeutic use[MESH] |COVID-19 Vaccines/immunology/*therapeutic use[MESH] |COVID-19/pathology/virology[MESH] |Humans[MESH] |Immunity, Innate/*drug effects[MESH] |Immunotherapy/trends[MESH] |Nanoparticles/chemistry/therapeutic use[MESH] |SARS-CoV-2/immunology/pathogenicity[MESH]Nanomedicinal delivery of stimulator of interferon genes agonists: rec(epmc).pdf DeepDyve Pubget Overpricing