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10.3389/fmed.2020.579406

http://scihub22266oqcxt.onion/10.3389/fmed.2020.579406
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suck abstract from ncbi


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pmid33251230      Front+Med+(Lausanne) 2020 ; 7 (ä): 579406
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  • Longitudinal Changes on Clinical Features in 28 Children With COVID-19 in Shenzhen, China #MMPMID33251230
  • Liao X; Liu J; He Z; Hu M; Xiao T; Wei L; Cai Q; Wang H; He Q; Liu L; Zhang Z
  • Front Med (Lausanne) 2020[]; 7 (ä): 579406 PMID33251230show ga
  • Objective: To investigate the clinical characteristics of children with coronavirus disease 2019 (COVID-19) and identify the occurrence of viral shedding of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) during follow-up. Methods: We retrospectively retrieved data from pediatric patients with COVID-19 from the Shenzhen Third People's Hospital in China. The dynamics of SARS-CoV-2 and antibodies against SARS-CoV-2 were analyzed during hospitalization and after discharge. Results: From January 23 to March 15, 2020, a total of 28 pediatric patients were diagnosed with COVID-19 and were followed for at least 1 month. The median age was 7 years (IQR 3.5-10) and none of the children progressed to severe COVID-19 during hospitalization. Ten patients tested positive for SARS-CoV-2 1 month after discharge while four patients tested positive during the 2nd month after discharge. Only three of 12 children showed detectable immunoglobulin-M (IgM) on day 5, 18, and 21 after illness onset, respectively. Conclusions: COVID-19 disease was relatively mild among children while a number did test positive after discharge from the hospital. Public health initiatives should thus adapt control measures targeted toward children.
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