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10.7883/yoken.JJID.2020.781

http://scihub22266oqcxt.onion/10.7883/yoken.JJID.2020.781
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33250495!ä!33250495

suck abstract from ncbi


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pmid33250495      Jpn+J+Infect+Dis 2021 ; 74 (4): 273-279
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  • Comparison of Clinical and Laboratory Features and Treatment Options of 237 Symptomatic and Asymptomatic Children Infected with SARS-CoV-2 in the Early Phase of the COVID-19 Pandemic in Turkey #MMPMID33250495
  • Soysal A; Gonullu E; Arslan H; Kibar BS; Pop S; Yurttas GN; Demirbacak H; Unal F; Oktem S; Atici S; Yucel Sen AD; Karabayir N; Karabocuoglu M
  • Jpn J Infect Dis 2021[Jul]; 74 (4): 273-279 PMID33250495show ga
  • Little is known about the therapeutic use of hydroxychloroquine in pediatric patients with coronavirus disease 2019 (COVID-19). Here, we retrospectively retrieved data of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) PCR-positive pediatric patients from 20 hospitals in 8 Turkish cities. We obtained epidemiological, clinical, and laboratory features of the patients, as well as the drugs used for treating COVID-19. A total of 237 nasopharyngeal swab SARS-CoV-2 PCR-positive children were included in the study from March 26, 2020 to June 20, 2020. The mean age of asymptomatic children (118 +/- 62 months) was higher than that of symptomatic children (89 +/- 69 months). Symptomatic children had significantly lower mean lymphocyte counts and higher mean CRP, D-dimer, procalcitonin, and LDH levels than asymptomatic children in the univariate analysis. Among 156 children, 78 (50%), 15, 44, and 21 were treated with a hydroxychloroquine-containing regimen, hydroxychloroquine + azithromycin + oseltamivir, hydroxychloroquine + azithromycin, and hydroxychloroquine alone, respectively. Among 156 patients who received medical treatment, 90 (58%) underwent pre- and/or post-treatment electrocardiogram (ECG). However, none of them had ECG abnormalities or required hydroxychloroquine discontinuation due to adverse drug reactions.
  • |*COVID-19 Drug Treatment[MESH]
  • |Adolescent[MESH]
  • |Antiviral Agents/*therapeutic use[MESH]
  • |Asymptomatic Infections[MESH]
  • |Child[MESH]
  • |Child, Preschool[MESH]
  • |Electrocardiography[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Hydroxychloroquine/therapeutic use[MESH]
  • |Infant[MESH]
  • |Infant, Newborn[MESH]
  • |Laboratories[MESH]
  • |Lymphocyte Count/methods[MESH]
  • |Male[MESH]
  • |Pandemics/*prevention & control[MESH]
  • |Retrospective Studies[MESH]
  • |SARS-CoV-2/*drug effects[MESH]


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