Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1016/j.cyto.2020.155365 http://scihub22266oqcxt.onion/10.1016/j.cyto.2020.155365 33246770!7651249!33246770     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cytokine 2021 ; 138 (ä): 155365 Nephropedia Template TP {{tp|p=33246770|t=2021. An inter-correlated cytokine network identified at the center of cytokine storm predicted COVID-19 prognosis |pdf=|usr=}}{{33246770}} gab.com Text An inter-correlated cytokine network identified at the center of cytokine storm predicted COVID-19 prognosis JO: Cytokine http://www.kidney.de/pget.php?&tw=1&pmid=33246770 #FOAvip The hyper-inflammatory response is thought to be a major cause of acute respiratory distress syndrome (ARDS) in patients with COVID-19. Although multiple cytokines are reportedly associated with disease severity, the key mediators of SARS-CoV-2 induced cytokine storm and their predictive values have not been fully elucidated. The present study analyzed maximal and early (within 10 days after disease onset) concentrations of 12-plex cytokines in plasma. We found consistently elevated plasma levels of IL-6, IL-8 and IL-5 in patients who were deceased compared with those who had mild/moderate or severe disease. The early plasma concentrations of IFN-a and IL-2 positively correlated with the length of the disease course. Moreover, correlation network analysis showed that IL-6, IL-8, and IL-5 located at the center of an inter-correlated cytokine network. These findings suggested that IL-8, IL-6, IL-5 might play central roles in cytokine storms associated with COVID-19 and that the early detection of multiple plasma cytokines might help to predict the prognosis of this disease. Twit Text FOAVip An inter-correlated cytokine network identified at the center of cytokine storm predicted COVID-19 prognosis ????Cytokine http://www.kidney.de/pget.php?&tw=1&pmid=33246770 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33246770 #FOAvip English Wikipedia <ref>{{Cite pmid|33246770}}</ref> An inter-correlated cytokine network identified at the center of cytokine storm predicted COVID-19 prognosis #MMPMID33246770 Liu Y; Chen D; Hou J; Li H; Cao D; Guo M; Ling Y; Gao M; Zhou Y; Wan Y; Zhu Z Cytokine 2021[Feb]; 138 (ä): 155365 PMID33246770show ga The hyper-inflammatory response is thought to be a major cause of acute respiratory distress syndrome (ARDS) in patients with COVID-19. Although multiple cytokines are reportedly associated with disease severity, the key mediators of SARS-CoV-2 induced cytokine storm and their predictive values have not been fully elucidated. The present study analyzed maximal and early (within 10 days after disease onset) concentrations of 12-plex cytokines in plasma. We found consistently elevated plasma levels of IL-6, IL-8 and IL-5 in patients who were deceased compared with those who had mild/moderate or severe disease. The early plasma concentrations of IFN-a and IL-2 positively correlated with the length of the disease course. Moreover, correlation network analysis showed that IL-6, IL-8, and IL-5 located at the center of an inter-correlated cytokine network. These findings suggested that IL-8, IL-6, IL-5 might play central roles in cytokine storms associated with COVID-19 and that the early detection of multiple plasma cytokines might help to predict the prognosis of this disease. |Aged[MESH] |COVID-19/*pathology[MESH] |Correlation of Data[MESH] |Cytokine Release Syndrome/*pathology[MESH] |Cytokines/*blood[MESH] |Female[MESH] |Humans[MESH] |Interferon-alpha/blood[MESH] |Interleukin-2/blood[MESH] |Interleukin-5/blood[MESH] |Interleukin-6/blood[MESH] |Interleukin-8/blood[MESH] |Male[MESH] |Middle Aged[MESH] |Prognosis[MESH] |Respiratory Distress Syndrome/*pathology[MESH] |Retrospective Studies[MESH] |SARS-CoV-2/*immunology[MESH]An inter-correlated cytokine network identified at the center of cytok(epmc).pdf DeepDyve Pubget Overpricing