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10.1007/s10096-020-04089-y http://scihub22266oqcxt.onion/10.1007/s10096-020-04089-y 33245471!7693853!33245471     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Eur+J+Clin+Microbiol+Infect+Dis 2021 ; 40 (2): 451-455 Nephropedia Template TP {{tp|p=33245471|t=2021. Expression and co-expression analyses of TMPRSS2, a key element in COVID-19 |pdf=|usr=}}{{33245471}} gab.com Text Expression and co-expression analyses of TMPRSS2, a key element in COVID-19 JO: Eur J Clin Microbiol Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=33245471 #FOAvip The ACE2 receptor is, so far, the best-known host factor for SARS-CoV-2 entry, but another essential element, the TMPRSS2 protease, has recently been identified. Here, we have analysed TMPRSS2 expression data in the lung correlating them with age, sex, diabetes, smoking habits, exposure to pollutant and other stimuli, in order to highlight which factors might alter TMPRSS2 expression, and thus impact the susceptibility to infection and COVID-19 prognosis. Moreover, we reported TMPRSS2 polymorphisms affecting its expression and suggested the ethnic groups more prone to COVID-19. Finally, we also highlighted a gender-specific co-expression between TMPRSS2 and other genes related to SARS-CoV-2 entry, maybe explaining the higher observed susceptibility of infection in men. Our results could be useful in designing potential prevention and treatment strategies regarding the COVID-19. Twit Text FOAVip Expression and co-expression analyses of TMPRSS2, a key element in COVID-19 ????Eur J Clin Microbiol Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=33245471 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33245471 #FOAvip English Wikipedia <ref>{{Cite pmid|33245471}}</ref> Expression and co-expression analyses of TMPRSS2, a key element in COVID-19 #MMPMID33245471 Piva F; Sabanovic B; Cecati M; Giulietti M Eur J Clin Microbiol Infect Dis 2021[Feb]; 40 (2): 451-455 PMID33245471show ga The ACE2 receptor is, so far, the best-known host factor for SARS-CoV-2 entry, but another essential element, the TMPRSS2 protease, has recently been identified. Here, we have analysed TMPRSS2 expression data in the lung correlating them with age, sex, diabetes, smoking habits, exposure to pollutant and other stimuli, in order to highlight which factors might alter TMPRSS2 expression, and thus impact the susceptibility to infection and COVID-19 prognosis. Moreover, we reported TMPRSS2 polymorphisms affecting its expression and suggested the ethnic groups more prone to COVID-19. Finally, we also highlighted a gender-specific co-expression between TMPRSS2 and other genes related to SARS-CoV-2 entry, maybe explaining the higher observed susceptibility of infection in men. Our results could be useful in designing potential prevention and treatment strategies regarding the COVID-19. |*SARS-CoV-2[MESH] |Aged[MESH] |COVID-19/*etiology[MESH] |Female[MESH] |Humans[MESH] |Lung/enzymology[MESH] |Male[MESH] |Polymorphism, Single Nucleotide[MESH] |Quantitative Trait Loci[MESH] |Serine Endopeptidases/*genetics/physiology[MESH]Expression and co-expression analyses of TMPRSS2, a key element in COV(epmc).pdf DeepDyve Pubget Overpricing