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10.1259/bjr.20200574

http://scihub22266oqcxt.onion/10.1259/bjr.20200574
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33245241!7774695!33245241
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suck abstract from ncbi


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pmid33245241      Br+J+Radiol 2021 ; 94 (1117): 20200574
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  • Structured reporting of chest CT provides high sensitivity and specificity for early diagnosis of COVID-19 in a clinical routine setting #MMPMID33245241
  • Gross A; Heine G; Schwarz M; Thiemig D; Glaser S; Albrecht T
  • Br J Radiol 2021[Jan]; 94 (1117): 20200574 PMID33245241show ga
  • OBJECTIVES: Although chest CT has been widely used in patients with COVID-19, its role for early diagnosis of COVID-19 is unclear. We report the diagnostic performance of chest CT using structured reporting in a routine clinical setting during the early phase of the epidemic in Germany. METHODS: Patients with clinical suspicion of COVID-19 and moderate-to-severe symptoms were included in this retrospective study. CTs were performed and reported before RT-PCR results (reference standard) became available. A structured reporting system was used that concluded in a recently described five-grade score ("CO-RADS"), indicating the level of suspicion for pulmonary involvement of COVID-19 from 1 = very low to 5 = very high. Structured reporting was performed by three Radiologists in consensus. RESULTS: In 96 consecutive patients (50 male, mean age 64), RT-PCR was positive in 20 (21%) cases. CT features significantly more common in RT-PCR-positive patients were ground-glass opacities as dominant feature, crazy paving, hazy margins of opacities, and multifocal bilateral distribution (p < 0.05). Using a cut-off point between CO-RADS 3 and 4, sensitivity was 90%, specificity 91%, positive predictive value 72%, negative predictive value 97%, and accuracy 91%. ROC analysis showed an AUC of 0.938. CONCLUSIONS: Structured reporting of chest CT with a five-grade scale provided accurate diagnosis of COVID-19. Its use was feasible and helpful in clinical routine. ADVANCES IN KNOWLEDGE: Chest CT with structured reporting may be a provisional diagnostic alternative to RT-PCR testing for early diagnosis of COVID-19, especially when RT-PCR results are delayed or test capacities are limited.
  • |*Tomography, X-Ray Computed/methods[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19/*diagnostic imaging[MESH]
  • |Early Diagnosis[MESH]
  • |Female[MESH]
  • |Germany[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Retrospective Studies[MESH]
  • |Sensitivity and Specificity[MESH]
  • |Severity of Illness Index[MESH]


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