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10.1038/s41598-020-77349-8 http://scihub22266oqcxt.onion/10.1038/s41598-020-77349-8 33244027!7692487!33244027     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Rep 2020 ; 10 (1): 20173 Nephropedia Template TP {{tp|p=33244027|t=2020. Daily inhalation of hydrogen gas has a blood pressure-lowering effect in a rat model of hypertension |pdf=|usr=}}{{33244027}} gab.com Text Daily inhalation of hydrogen gas has a blood pressure-lowering effect in a rat model of hypertension JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=33244027 #FOAvip A recent clinical study demonstrated that haemodialysis with a dialysate containing hydrogen (H(2)) improves blood pressure control in end-stage kidney disease. Herein, we examined whether H(2) has a salutary effect on hypertension in animal models. We subjected 5/6 nephrectomised rats to inhalation of either H(2) (1.3% H(2) + 21% O(2) + 77.7% N(2)) or control (21% O(2) + 79% N(2)) gas mixture for 1 h per day. H(2) significantly suppressed increases in blood pressure after 5/6 nephrectomy. The anti-hypertensive effect of H(2) was also confirmed in rats in a stable hypertensive state 3 weeks after nephrectomy. To examine the detailed effects of H(2) on hypertension, we used an implanted telemetry system to continuously monitor blood pressure. H(2) exerted an anti-hypertensive effect not only during daytime rest, but also during night-time activities. Spectral analysis of blood pressure variability revealed that H(2) improved autonomic imbalance, namely by suppressing the overly active sympathetic nervous system and augmenting parasympathetic nervous system activity; these effects co-occurred with the blood pressure-lowering effect. In conclusion, 1-h daily exposure to H(2) exerts an anti-hypertensive effect in an animal model of hypertension. Twit Text FOAVip Daily inhalation of hydrogen gas has a blood pressure-lowering effect in a rat model of hypertension ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=33244027 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33244027 #FOAvip English Wikipedia <ref>{{Cite pmid|33244027}}</ref> Daily inhalation of hydrogen gas has a blood pressure-lowering effect in a rat model of hypertension #MMPMID33244027 Sugai K; Tamura T; Sano M; Uemura S; Fujisawa M; Katsumata Y; Endo J; Yoshizawa J; Homma K; Suzuki M; Kobayashi E; Sasaki J; Hakamata Y Sci Rep 2020[Nov]; 10 (1): 20173 PMID33244027show ga A recent clinical study demonstrated that haemodialysis with a dialysate containing hydrogen (H(2)) improves blood pressure control in end-stage kidney disease. Herein, we examined whether H(2) has a salutary effect on hypertension in animal models. We subjected 5/6 nephrectomised rats to inhalation of either H(2) (1.3% H(2) + 21% O(2) + 77.7% N(2)) or control (21% O(2) + 79% N(2)) gas mixture for 1 h per day. H(2) significantly suppressed increases in blood pressure after 5/6 nephrectomy. The anti-hypertensive effect of H(2) was also confirmed in rats in a stable hypertensive state 3 weeks after nephrectomy. To examine the detailed effects of H(2) on hypertension, we used an implanted telemetry system to continuously monitor blood pressure. H(2) exerted an anti-hypertensive effect not only during daytime rest, but also during night-time activities. Spectral analysis of blood pressure variability revealed that H(2) improved autonomic imbalance, namely by suppressing the overly active sympathetic nervous system and augmenting parasympathetic nervous system activity; these effects co-occurred with the blood pressure-lowering effect. In conclusion, 1-h daily exposure to H(2) exerts an anti-hypertensive effect in an animal model of hypertension. |Administration, Inhalation[MESH] |Animals[MESH] |Antihypertensive Agents/therapeutic use[MESH] |Blood Pressure Determination[MESH] |Blood Pressure/*drug effects[MESH] |Disease Models, Animal[MESH] |Hydrogen/administration & dosage/*pharmacology[MESH] |Hypertension/*drug therapy[MESH] |Male[MESH] |Rats[MESH] |Rats, Inbred Lew[MESH]Daily inhalation of hydrogen gas has a blood pressure-lowering effect (epmc).pdf DeepDyve Pubget Overpricing