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10.1177/0004563220980495 http://scihub22266oqcxt.onion/10.1177/0004563220980495 33242972!ä!33242972 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Ann+Clin+Biochem 2021 ; 58 (2): 149-152 Nephropedia Template TP {{tp|p=33242972|t=2021. SARS-CoV-2 immunochromatographic IgM/IgG rapid test in pregnancy: A false friend?|pdf=|usr=}}{{33242972}} gab.com Text SARS-CoV-2 immunochromatographic IgM/IgG rapid test in pregnancy: A false friend JO: Ann Clin Biochem http://www.kidney.de/pget.php?&tw=1&pmid=33242972 #FOAvip BACKGROUND: An increasing body of evidence has revealed that SARS-CoV-2 infection in pregnant women could increase the risk of adverse maternal and fetal outcomes. Careful monitoring of pregnancies with COVID-19 and measures to prevent neonatal infection are warranted. Therefore, rapid antibody tests have been suggested as an efficient screening tool during pregnancy. CASES: We analysed the clinical performance during pregnancy of a rapid, lateral-flow immunochromatographic assay for qualitative detection of SARS-CoV-2 IgG/IgM antibodies. We performed a universal screening including 169 patients during their last trimester of pregnancy. We present a series of 14 patients with positive SARS-CoV-2 immunochromatographic assay rapid test result. Immunochromatographic assay results were always confirmed by chemiluminescent microparticle immunoassays for quantitative detection of SARS-CoV-2 IgG and IgM+IgA antibodies as the gold standard. We observed a positive predictive value of 50% and a false positive rate of 50% in pregnant women, involving a significantly lower diagnostic performance than reported in non-pregnant patients. DISCUSSION: Our data suggest that although immunochromatographic assay rapid tests may be a fast and profitable screening tool for SARS-CoV-2 infection, they may have a high false positive rate and low positive predictive value in pregnant women. Therefore, immunochromatographic assay for qualitative detection of SARS-CoV-2 IgG/IgM antibodies must be verified by other test in pregnant patients. Twit Text FOAVip SARS-CoV-2 immunochromatographic IgM/IgG rapid test in pregnancy: A false friend ????Ann Clin Biochem http://www.kidney.de/pget.php?&tw=1&pmid=33242972 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33242972 #FOAvip English Wikipedia <ref>{{Cite pmid|33242972}}</ref> SARS-CoV-2 immunochromatographic IgM/IgG rapid test in pregnancy: A false friend? #MMPMID33242972 Fabre M; Ruiz-Martinez S; Monserrat Cantera ME; Cortizo Garrido A; Beunza Fabra Z; Peran M; Benito R; Mateo P; Paules C; Oros D Ann Clin Biochem 2021[Mar]; 58 (2): 149-152 PMID33242972show ga BACKGROUND: An increasing body of evidence has revealed that SARS-CoV-2 infection in pregnant women could increase the risk of adverse maternal and fetal outcomes. Careful monitoring of pregnancies with COVID-19 and measures to prevent neonatal infection are warranted. Therefore, rapid antibody tests have been suggested as an efficient screening tool during pregnancy. CASES: We analysed the clinical performance during pregnancy of a rapid, lateral-flow immunochromatographic assay for qualitative detection of SARS-CoV-2 IgG/IgM antibodies. We performed a universal screening including 169 patients during their last trimester of pregnancy. We present a series of 14 patients with positive SARS-CoV-2 immunochromatographic assay rapid test result. Immunochromatographic assay results were always confirmed by chemiluminescent microparticle immunoassays for quantitative detection of SARS-CoV-2 IgG and IgM+IgA antibodies as the gold standard. We observed a positive predictive value of 50% and a false positive rate of 50% in pregnant women, involving a significantly lower diagnostic performance than reported in non-pregnant patients. DISCUSSION: Our data suggest that although immunochromatographic assay rapid tests may be a fast and profitable screening tool for SARS-CoV-2 infection, they may have a high false positive rate and low positive predictive value in pregnant women. Therefore, immunochromatographic assay for qualitative detection of SARS-CoV-2 IgG/IgM antibodies must be verified by other test in pregnant patients. |*COVID-19 Serological Testing[MESH] |*COVID-19/diagnosis/immunology[MESH] |*Pregnancy Complications, Infectious/diagnosis/immunology[MESH] |Adult[MESH] |Antibodies, Viral/*immunology[MESH] |Female[MESH] |Humans[MESH] |Immunoassay[MESH] |Immunoglobulin G/*immunology[MESH] |Immunoglobulin M/*immunology[MESH] |Pregnancy[MESH]SARS-CoV-2 immunochromatographic IgM/IgG rapid test in pregnancy: A fa(epmc).pdf DeepDyve Pubget Overpricing