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Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 J+Glob+Antimicrob+Resist 2021 ; 24 (ä): 90-92 Nephropedia Template TP
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Cytokine storm of a different flavour: The different cytokine signature of SARS-CoV-2, the cause of COVID-19, from the original SARS outbreak #MMPMID33242672
Griffin DO; Jensen A; Khan M; Chin J; Chin K; Saad J; Parnell R; Awwad C; Patel D
J Glob Antimicrob Resist 2021[Mar]; 24 (ä): 90-92 PMID33242672show ga
Here we present a case series of three patients with COVID-19 (coronavirus disease 2019) who had a cytokine panel that revealed elevation of interleukin-6 (IL-6) but normal levels of interleukin-10 (IL-10), interferon-gamma (INF-gamma) and interleukin-8 (IL-8), in contrast to the cytokine signature described in severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). We also documented evidence of a compromised T-cell IFN-gamma response in two of these patients.