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10.1093/milmed/usaa508

http://scihub22266oqcxt.onion/10.1093/milmed/usaa508
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33242097!7717316!33242097
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suck abstract from ncbi


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pmid33242097      Mil+Med 2021 ; 186 (1-2): e270-e276
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  • Multisystem Inflammatory Syndrome in Children during the COVID-19 Pandemic: A Case Report on Managing the Hyperinflammation #MMPMID33242097
  • Cirks BT; Geracht JC; Jones OY; May JW; Mikita CP; Rajnik M; Helfrich AM
  • Mil Med 2021[Jan]; 186 (1-2): e270-e276 PMID33242097show ga
  • The novel human coronavirus of 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has quickly swept throughout the entire world. As the ongoing pandemic has spread, recent studies have described children presenting with a multisystem inflammatory disorder sharing the features of Kawasaki disease (KD) and toxic shock syndrome, now named Multisystem Inflammatory Syndrome in Children (MIS-C). These cases report a similar phenotype of prolonged fever, multisystem involvement, and biomarkers demonstrating marked hyperinflammation that occurs temporally in association with local community spread of SARS-CoV-2. Herein, we describe the presentation, clinical characteristics, and management of an 11-year-old boy with prolonged fever, strikingly elevated inflammatory markers, and profound, early coronary artery aneurysm consistent with a hyperinflammatory, multisystem disease temporally associated with coronavirus disease 2019. We highlight our multidisciplinary team's management with intravenous immunoglobulin, methylprednisolone, and an interleukin-1 receptor antagonist, anakinra, as a strategy to manage this multisystem, hyperinflammatory disease process.
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