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10.1590/1678-4685-GMB-2020-0197 http://scihub22266oqcxt.onion/10.1590/1678-4685-GMB-2020-0197 33237151!7731900!33237151     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Genet+Mol+Biol 2020 ; 44 (1 Suppl 1): e20200197 Nephropedia Template TP {{tp|p=33237151|t=2020. Host-shift as the cause of emerging infectious diseases: Experimental approaches using Drosophila-virus interactions |pdf=|usr=}}{{33237151}} gab.com Text Host-shift as the cause of emerging infectious diseases: Experimental approaches using Drosophila-virus interactions JO: Genet Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=33237151 #FOAvip Host shifts, when a cross-species transmission of a pathogen can lead to successful infections, are the main cause of emerging infectious diseases, such as COVID-19. A complex challenge faced by the scientific community is to address the factors that determine whether the cross-species transmissions will result in spillover or sustained onwards infections. Here we review recent literature and present a perspective on current approaches we are using to understand the mechanisms underlying host shifts. We highlight the usefulness of the interactions between Drosophila species and viruses as an ideal study model. Additionally, we discuss how cross-infection experiments - when pathogens from a natural reservoir are intentionally injected in novel host species- can test the effect cross-species transmissions may have on the fitness of virus and host, and how the host phylogeny may influence this response. We also discuss experiments evaluating how cooccurrence with other viruses or the presence of the endosymbiont bacteria Wolbachia may affect the performance of new viruses in a novel host. Finally, we discuss the need of surveys of virus diversity in natural populations using next-generation sequencing technologies. In the long term, these approaches can contribute to a better understanding of the basic biology of host shifts. Twit Text FOAVip Host-shift as the cause of emerging infectious diseases: Experimental approaches using Drosophila-virus interactions ????Genet Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=33237151 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33237151 #FOAvip English Wikipedia <ref>{{Cite pmid|33237151}}</ref> Host-shift as the cause of emerging infectious diseases: Experimental approaches using Drosophila-virus interactions #MMPMID33237151 Pimentel AC; Beraldo CS; Cogni R Genet Mol Biol 2020[]; 44 (1 Suppl 1): e20200197 PMID33237151show ga Host shifts, when a cross-species transmission of a pathogen can lead to successful infections, are the main cause of emerging infectious diseases, such as COVID-19. A complex challenge faced by the scientific community is to address the factors that determine whether the cross-species transmissions will result in spillover or sustained onwards infections. Here we review recent literature and present a perspective on current approaches we are using to understand the mechanisms underlying host shifts. We highlight the usefulness of the interactions between Drosophila species and viruses as an ideal study model. Additionally, we discuss how cross-infection experiments - when pathogens from a natural reservoir are intentionally injected in novel host species- can test the effect cross-species transmissions may have on the fitness of virus and host, and how the host phylogeny may influence this response. We also discuss experiments evaluating how cooccurrence with other viruses or the presence of the endosymbiont bacteria Wolbachia may affect the performance of new viruses in a novel host. Finally, we discuss the need of surveys of virus diversity in natural populations using next-generation sequencing technologies. In the long term, these approaches can contribute to a better understanding of the basic biology of host shifts. äHost-shift as the cause of emerging infectious diseases: Experimental (epmc).pdf DeepDyve Pubget Overpricing