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10.7554/eLife.61981 http://scihub22266oqcxt.onion/10.7554/eLife.61981 33231169!7685703!33231169     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33231169&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\33231169.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Elife 2020 ; 9 (ä): ä Nephropedia Template TP {{tp|p=33231169|t=2020. COVID-19 research risks ignoring important host genes due to pre-established research patterns |pdf=|usr=}}{{33231169}} gab.com Text COVID-19 research risks ignoring important host genes due to pre-established research patterns JO: Elife http://www.kidney.de/pget.php?&tw=1&pmid=33231169 #FOAvip It is known that research into human genes is heavily skewed towards genes that have been widely studied for decades, including many genes that were being studied before the productive phase of the Human Genome Project. This means that the genes most frequently investigated by the research community tend to be only marginally more important to human physiology and disease than a random selection of genes. Based on an analysis of 10,395 research publications about SARS-CoV-2 that mention at least one human gene, we report here that the COVID-19 literature up to mid-October 2020 follows a similar pattern. This means that a large number of host genes that have been implicated in SARS-CoV-2 infection by four genome-wide studies remain unstudied. While quantifying the consequences of this neglect is not possible, they could be significant. Twit Text FOAVip COVID-19 research risks ignoring important host genes due to pre-established research patterns ????Elife http://www.kidney.de/pget.php?&tw=1&pmid=33231169 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33231169 #FOAvip English Wikipedia <ref>{{Cite pmid|33231169}}</ref> COVID-19 research risks ignoring important host genes due to pre-established research patterns #MMPMID33231169 Stoeger T; Nunes Amaral LA Elife 2020[Nov]; 9 (ä): ä PMID33231169show ga It is known that research into human genes is heavily skewed towards genes that have been widely studied for decades, including many genes that were being studied before the productive phase of the Human Genome Project. This means that the genes most frequently investigated by the research community tend to be only marginally more important to human physiology and disease than a random selection of genes. Based on an analysis of 10,395 research publications about SARS-CoV-2 that mention at least one human gene, we report here that the COVID-19 literature up to mid-October 2020 follows a similar pattern. This means that a large number of host genes that have been implicated in SARS-CoV-2 infection by four genome-wide studies remain unstudied. While quantifying the consequences of this neglect is not possible, they could be significant. |COVID-19/*genetics/metabolism/virology[MESH] |Gene Ontology[MESH] |Genome, Human/*genetics[MESH] |Genome-Wide Association Study[MESH] |Host Microbial Interactions/*genetics[MESH] |Humans[MESH] |Pandemics[MESH] |Publications[MESH]COVID-19 research risks ignoring important host genes due to pre-estab(epmc).pdf DeepDyve Pubget Overpricing