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Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 IJU+Case+Rep 2021 ; 4 (1): 22-24 Nephropedia Template TP
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Successful recovery from coronavirus disease 2019 in a living kidney transplant recipient using low-dose methylprednisolone #MMPMID33230502
Tanaka R; Kakuta Y; Tsutahara K; Nakagawa M; Ichimaru N; Sakaguchi K; Kato T; Imamura R; Nonomura N; Takao T
IJU Case Rep 2021[Jan]; 4 (1): 22-24 PMID33230502show ga
INTRODUCTION: The data of immunosuppressive therapy management on solid organ transplant recipients with coronavirus disease 2019 are insufficient. We report a kidney transplant recipient who developed coronavirus disease 2019 pneumonia, with successful management of low-dose mPSL. CASE PRESENTATION: A 36-year-old man, who underwent living kidney transplantation 1.5 year prior, developed fever. After 10 days, he developed dyspnea, and his blood oxygen levels decreased. Computed tomography showed pulmonary ground-glass shadow on both lungs, and the coronavirus disease 2019 real-time polymerase chain reaction test was positive. After reducing the immunosuppressive agents, the C-reactive protein levels continued elevating, and the pulmonary shadow spread. Subsequently, low-dose methylprednisolone (40 mg/day) was administered for 4 days and his C-reactive protein and blood oxygen levels increased and improved, respectively. The coronavirus disease 2019 real-time polymerase chain reaction test was negative and the pulmonary shadow disappeared. CONCLUSION: Low-dose methylprednisolone may prevent the development of severe coronavirus disease 2019.