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10.1016/j.tem.2020.11.004

http://scihub22266oqcxt.onion/10.1016/j.tem.2020.11.004
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33229187!7649655!33229187
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suck abstract from ncbi


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pmid33229187      Trends+Endocrinol+Metab 2021 ; 32 (1): 3-6
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  • Sex and COVID-19: A Protective Role for Reproductive Steroids #MMPMID33229187
  • Pinna G
  • Trends Endocrinol Metab 2021[Jan]; 32 (1): 3-6 PMID33229187show ga
  • Evidence shows coronavirus disease 2019 (COVID-19)-induced symptom severity and mortality is more frequent in men than in women, suggesting sex steroids may play a protective role. Female reproductive steroids, estrogen and progesterone, and its metabolite allopregnanolone, are anti-inflammatory, reshape competence of immune cells, stimulate antibody production, and promote proliferation and repair of respiratory epithelial cells, suggesting they may protect against COVID-19 symptoms.
  • |Age Factors[MESH]
  • |Animals[MESH]
  • |COVID-19/*immunology/metabolism[MESH]
  • |Estradiol/*immunology/metabolism[MESH]
  • |Estrogens/*immunology/metabolism[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Immune System/*immunology/metabolism[MESH]
  • |Inflammation/*immunology/metabolism[MESH]
  • |Male[MESH]
  • |Pregnanolone/*immunology/metabolism[MESH]
  • |Pregnenolone/*immunology/metabolism[MESH]
  • |Progesterone/*immunology/metabolism[MESH]
  • |Sex Factors[MESH]


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