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10.1016/j.mgene.2020.100831 http://scihub22266oqcxt.onion/10.1016/j.mgene.2020.100831 33224734!7672338!33224734     free     free     free       Meta+Gene 2021 ; 27 (?): 100831 Nephropedia Template TP {{tp|p=33224734|t=2021. Therapeutic potential of miRNAs targeting SARS-CoV-2 host cell receptor ACE2 |pdf=|usr=}}{{33224734}} gab.com Text Therapeutic potential of miRNAs targeting SARS-CoV-2 host cell receptor ACE2 JO: Meta Gene http://www.kidney.de/pget.php?&tw=1&pmid=33224734 #FOAvip In late December 2019, several cases of pneumonia of unknown etiology (COVID-19) were reported in Wuhan, Hubei province, China. Based on clinical findings, blood tests and chest radiographs, this disease was diagnosed as a virus-associated pneumonia. Sequence analysis revealed a novel coronavirus, called SARS-CoV-2 (formerly called 2019-nCoV), as the causative agent of pneumonia of unknown etiology. So far, the SARS-CoV-2 infection continues to spread, and this virus poses a serious public health threat. In this study, it was aimed to reveal potential miRNA targets for the regulation of SARS-CoV-2 host cell receptor ACE2. For the identification of potential miRNA targets for the ACE2 gene, TarBase v.8 (DIANA Tools), TargetScan, miRTarBase and miRDB miRNA-target prediction algorithms were used. FANTOM5 CAGE was used for the cellular ontology analysis. Expression levels of these miRNAs were determined using OncomiR Pan-Cancer miRNome Atlas. The results suggest that members of miR-200 family of miRNAs, especially miR-200c-3p, are strong candidate targets for the regulation of ACE2 in respiratory system cells. Consequently, the present study for the first time emphasizes potential use of miRNA-based therapeutics in the battle against SARS-CoV-2 infection and its deadly disease, COVID-19. Twit Text FOAVip Therapeutic potential of miRNAs targeting SARS-CoV-2 host cell receptor ACE2 ????Meta Gene http://www.kidney.de/pget.php?&tw=1&pmid=33224734 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33224734 #FOAvip English Wikipedia <ref>{{Cite pmid|33224734}}</ref> Therapeutic potential of miRNAs targeting SARS-CoV-2 host cell receptor ACE2 #MMPMID33224734 Bozgeyik I Meta Gene 2021[Feb]; 27 (?): 100831 PMID33224734show ga In late December 2019, several cases of pneumonia of unknown etiology (COVID-19) were reported in Wuhan, Hubei province, China. Based on clinical findings, blood tests and chest radiographs, this disease was diagnosed as a virus-associated pneumonia. Sequence analysis revealed a novel coronavirus, called SARS-CoV-2 (formerly called 2019-nCoV), as the causative agent of pneumonia of unknown etiology. So far, the SARS-CoV-2 infection continues to spread, and this virus poses a serious public health threat. In this study, it was aimed to reveal potential miRNA targets for the regulation of SARS-CoV-2 host cell receptor ACE2. For the identification of potential miRNA targets for the ACE2 gene, TarBase v.8 (DIANA Tools), TargetScan, miRTarBase and miRDB miRNA-target prediction algorithms were used. FANTOM5 CAGE was used for the cellular ontology analysis. Expression levels of these miRNAs were determined using OncomiR Pan-Cancer miRNome Atlas. The results suggest that members of miR-200 family of miRNAs, especially miR-200c-3p, are strong candidate targets for the regulation of ACE2 in respiratory system cells. Consequently, the present study for the first time emphasizes potential use of miRNA-based therapeutics in the battle against SARS-CoV-2 infection and its deadly disease, COVID-19. ?Therapeutic potential of miRNAs targeting SARS-CoV-2 host cell recepto(epmc).pdf DeepDyve Pubget Overpricing