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10.14740/cr1159 http://scihub22266oqcxt.onion/10.14740/cr1159 33224386!7666590!33224386     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33224386&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Cardiol+Res 2020 ; 11 (6): 398-404 Nephropedia Template TP {{tp|p=33224386|t=2020. Cardiac Troponin-I and COVID-19: A Prognostic Tool for In-Hospital Mortality |pdf=|usr=}}{{33224386}} gab.com Text Cardiac Troponin-I and COVID-19: A Prognostic Tool for In-Hospital Mortality JO: Cardiol Res http://www.kidney.de/pget.php?&tw=1&pmid=33224386 #FOAvip BACKGROUND: The number of fatalities due to coronavirus disease 2019 (COVID-19) is escalating with more than 800,000 deaths globally. The scientific community remains in urgent need of prognostic tools to determine the probability of survival in patients with COVID-19 and to determine the need for hospitalization. METHODS: This is a retrospective cohort study of patients with a diagnosis of COVID-19 admitted to a tertiary center between March 2020 and July 2020. Patients age 18 years and older were stratified into two groups based on their troponin-I level in the first 24 h of admission (groups: elevated vs. normal). The aim of the study is to explore the utility of cardiac troponin-I level for early prognostication of patients with COVID-19. RESULTS: This cohort of 257 patients included 122/257 (47%) women with a mean age of 63 +/- 17 years. Patients with an elevated troponin-I level were more likely to be older (77 +/- 13 vs. 58 +/- 16 years, P < 0.0001), have a history of hypertension (P < 0.0001), diabetes mellitus (P = 0.0019), atrial fibrillation or flutter (P = 0.0009), coronary artery disease (P < 0.0001), and chronic heart failure (P = 0.0011). Patients with an elevated troponin-I level in the first 24 h of admission were more likely to have higher in-hospital mortality (52% vs. 10%, P < 0.0001). Troponin-I level in the first 24 h of admission had a negative predictive value of 89.7% and a positive predictive value of 51.9% for all-cause in-hospital mortality. CONCLUSIONS: Troponin-I elevation is commonly seen in patients with COVID-19 and is significantly associated with fatal outcomes. However, a normal troponin-I level in the first 24 h of admission had a high negative predictive value for all-cause in-hospital mortality, thereby predicting favorable survival at the time of discharge. Twit Text FOAVip Cardiac Troponin-I and COVID-19: A Prognostic Tool for In-Hospital Mortality ????Cardiol Res http://www.kidney.de/pget.php?&tw=1&pmid=33224386 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33224386 #FOAvip English Wikipedia <ref>{{Cite pmid|33224386}}</ref> Cardiac Troponin-I and COVID-19: A Prognostic Tool for In-Hospital Mortality #MMPMID33224386 Al Abbasi B; Torres P; Ramos-Tuarez F; Dewaswala N; Abdallah A; Chen K; Abdul Qader M; Job R; Aboulenain S; Dziadkowiec K; Bhopalwala H; Pino JE; Chait RD Cardiol Res 2020[Dec]; 11 (6): 398-404 PMID33224386show ga BACKGROUND: The number of fatalities due to coronavirus disease 2019 (COVID-19) is escalating with more than 800,000 deaths globally. The scientific community remains in urgent need of prognostic tools to determine the probability of survival in patients with COVID-19 and to determine the need for hospitalization. METHODS: This is a retrospective cohort study of patients with a diagnosis of COVID-19 admitted to a tertiary center between March 2020 and July 2020. Patients age 18 years and older were stratified into two groups based on their troponin-I level in the first 24 h of admission (groups: elevated vs. normal). The aim of the study is to explore the utility of cardiac troponin-I level for early prognostication of patients with COVID-19. RESULTS: This cohort of 257 patients included 122/257 (47%) women with a mean age of 63 +/- 17 years. Patients with an elevated troponin-I level were more likely to be older (77 +/- 13 vs. 58 +/- 16 years, P < 0.0001), have a history of hypertension (P < 0.0001), diabetes mellitus (P = 0.0019), atrial fibrillation or flutter (P = 0.0009), coronary artery disease (P < 0.0001), and chronic heart failure (P = 0.0011). Patients with an elevated troponin-I level in the first 24 h of admission were more likely to have higher in-hospital mortality (52% vs. 10%, P < 0.0001). Troponin-I level in the first 24 h of admission had a negative predictive value of 89.7% and a positive predictive value of 51.9% for all-cause in-hospital mortality. CONCLUSIONS: Troponin-I elevation is commonly seen in patients with COVID-19 and is significantly associated with fatal outcomes. However, a normal troponin-I level in the first 24 h of admission had a high negative predictive value for all-cause in-hospital mortality, thereby predicting favorable survival at the time of discharge. ?Cardiac Troponin-I and COVID-19: A Prognostic Tool for In-Hospital Mor(epmc).pdf DeepDyve Pubget Overpricing