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10.1016/j.molstruc.2020.129649

http://scihub22266oqcxt.onion/10.1016/j.molstruc.2020.129649
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33223566!7668221!33223566
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suck abstract from ncbi

pmid33223566      J+Mol+Struct 2021 ; 1230 (?): 129649
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  • Synthesis of potentially new schiff bases of N-substituted-2-quinolonylacetohydrazides as anti-COVID-19 agents #MMPMID33223566
  • Alshammari MB; Ramadan M; Aly AA; El-Sheref EM; Bakht MA; Ibrahim MAA; Shawky AM
  • J Mol Struct 2021[Apr]; 1230 (?): 129649 PMID33223566show ga
  • We report herein a new series of synthesized N-substituted-2-quinolonylacetohydrazides aiming to evaluate their activity towards SARS-CoV-2. The structures of the obtained products were fully confirmed by NMR, mass, IR spectra and elemental analysis as well. Molecular docking calculations showed that most of the tested compounds possessed good binding affinity to the SARS-CoV-2 main protease (M(pro)) comparable toRemdesivir.
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