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10.1016/j.diagmicrobio.2020.115257

http://scihub22266oqcxt.onion/10.1016/j.diagmicrobio.2020.115257
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33220640!7577894!33220640
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suck abstract from ncbi


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pmid33220640      Diagn+Microbiol+Infect+Dis 2021 ; 99 (3): 115257
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  • Prospective clinical validation of 3D printed nasopharyngeal swabs for diagnosis of COVID-19 #MMPMID33220640
  • Oland G; Garner O; de St Maurice A
  • Diagn Microbiol Infect Dis 2021[Mar]; 99 (3): 115257 PMID33220640show ga
  • COVID-19 greatly disrupted the global supply chain of nasopharyngeal swabs, and thus new products have come to market with little data to support their use. In this prospective study, 2 new 3D printed nasopharyngeal swab designs were evaluated against the standard, flocked nasopharyngeal swab for the diagnosis of COVID-19. Seventy adult patients (37 COVID-positive and 33 COVID-negative) underwent consecutive diagnostic reverse transcription polymerase chain reaction testing, with a flocked swab followed by one or two 3D printed swabs. The "Lattice Swab" (manufacturer Resolution Medical) demonstrated 93.3% sensitivity (95% CI, 77.9%-99.2%) and 96.8% specificity (83.3%-99.9%), yielding kappa?=?0.90 (0.85-0.96). The "Origin KXG" (manufacturer Origin Laboratories) demonstrated 83.9% sensitivity (66.3%-94.6%) and 100% specificity (88.8%-100.0%), yielding kappa?=?0.84 (0.77-0.91). Both 3D printed nasopharyngeal swab results have high concordance with the control swab results. The decision to use 3D printed nasopharyngeal swabs during the COVID-19 pandemic should be strongly considered by clinical and research laboratories.
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19 Testing/*instrumentation[MESH]
  • |COVID-19/*diagnosis/virology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Nasopharynx/*virology[MESH]
  • |Printing, Three-Dimensional/*instrumentation[MESH]
  • |SARS-CoV-2/*isolation & purification[MESH]
  • |Specimen Handling/*instrumentation/methods[MESH]


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