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10.1126/sciadv.abd5393 http://scihub22266oqcxt.onion/10.1126/sciadv.abd5393 33219112!7775777!33219112     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33219112&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Adv 2021 ; 7 (1): ä Nephropedia Template TP {{tp|p=33219112|t=2021. Test sensitivity is secondary to frequency and turnaround time for COVID-19 screening |pdf=|usr=}}{{33219112}} gab.com Text Test sensitivity is secondary to frequency and turnaround time for COVID-19 screening JO: Sci Adv http://www.kidney.de/pget.php?&tw=1&pmid=33219112 #FOAvip The COVID-19 pandemic has created a public health crisis. Because SARS-CoV-2 can spread from individuals with presymptomatic, symptomatic, and asymptomatic infections, the reopening of societies and the control of virus spread will be facilitated by robust population screening, for which virus testing will often be central. After infection, individuals undergo a period of incubation during which viral titers are too low to detect, followed by exponential viral growth, leading to peak viral load and infectiousness and ending with declining titers and clearance. Given the pattern of viral load kinetics, we model the effectiveness of repeated population screening considering test sensitivities, frequency, and sample-to-answer reporting time. These results demonstrate that effective screening depends largely on frequency of testing and speed of reporting and is only marginally improved by high test sensitivity. We therefore conclude that screening should prioritize accessibility, frequency, and sample-to-answer time; analytical limits of detection should be secondary. Twit Text FOAVip Test sensitivity is secondary to frequency and turnaround time for COVID-19 screening ????Sci Adv http://www.kidney.de/pget.php?&tw=1&pmid=33219112 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33219112 #FOAvip English Wikipedia <ref>{{Cite pmid|33219112}}</ref> Test sensitivity is secondary to frequency and turnaround time for COVID-19 screening #MMPMID33219112 Larremore DB; Wilder B; Lester E; Shehata S; Burke JM; Hay JA; Tambe M; Mina MJ; Parker R Sci Adv 2021[Jan]; 7 (1): ä PMID33219112show ga The COVID-19 pandemic has created a public health crisis. Because SARS-CoV-2 can spread from individuals with presymptomatic, symptomatic, and asymptomatic infections, the reopening of societies and the control of virus spread will be facilitated by robust population screening, for which virus testing will often be central. After infection, individuals undergo a period of incubation during which viral titers are too low to detect, followed by exponential viral growth, leading to peak viral load and infectiousness and ending with declining titers and clearance. Given the pattern of viral load kinetics, we model the effectiveness of repeated population screening considering test sensitivities, frequency, and sample-to-answer reporting time. These results demonstrate that effective screening depends largely on frequency of testing and speed of reporting and is only marginally improved by high test sensitivity. We therefore conclude that screening should prioritize accessibility, frequency, and sample-to-answer time; analytical limits of detection should be secondary. |*COVID-19 Nucleic Acid Testing[MESH] |*Viral Load[MESH] |Asymptomatic Infections[MESH] |COVID-19/*diagnosis[MESH] |Calibration[MESH] |Computer Simulation[MESH] |Epidemics[MESH] |Humans[MESH] |Kinetics[MESH] |Limit of Detection[MESH] |Mass Screening/*methods[MESH] |Models, Theoretical[MESH] |Polymerase Chain Reaction[MESH] |Reproducibility of Results[MESH] |Sensitivity and Specificity[MESH]Test sensitivity is secondary to frequency and turnaround time for COV(epmc).pdf DeepDyve Pubget Overpricing