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10.1016/j.amjcard.2020.11.009 http://scihub22266oqcxt.onion/10.1016/j.amjcard.2020.11.009 33217345!7671934!33217345     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33217345&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Am+J+Cardiol 2021 ; 141 (?): 140-146 Nephropedia Template TP {{tp|p=33217345|t=2021. Meta-analysis Comparing Outcomes in Patients With and Without Cardiac Injury and Coronavirus Disease 2019 (COVID 19) |pdf=|usr=}}{{33217345}} gab.com Text Meta-analysis Comparing Outcomes in Patients With and Without Cardiac Injury and Coronavirus Disease 2019 (COVID 19) JO: Am J Cardiol http://www.kidney.de/pget.php?&tw=1&pmid=33217345 #FOAvip Current evidence is limited to small studies describing the association between cardiac injury and outcomes in patients with coronavirus disease 2019 (COVID-19). To address this, we performed a comprehensive meta-analysis of studies in COVID-19 patients to evaluate the association between cardiac injury and all-cause mortality, intensive care unit (ICU) admission, mechanical ventilation, acute respiratory distress syndrome, acute kidney injury and coagulopathy. Further, studies comparing cardiac biomarker levels in survivors versus nonsurvivors were included. A total of 14 studies (3,175 patients) were utilized for the final analysis. Cardiac injury in patients with COVID-19 was associated with higher risk of mortality (risk ratio [RR]:7.79; 95% confidence interval [CI]: 4.69 to 13.01; I(2)=58%), ICU admission (RR: 4.06; 95% CI: 1.50 to 10.97; I(2)?=?61%), mechanical ventilation (RR: 5.53; 95% CI: 3.09 to 9.91; I(2)?=?0%), and developing coagulopathy (RR: 3.86; 95% CI:2.81 to 5.32; I(2)?=?0%). However, cardiac injury was not associated with increased risk of acute respiratory distress syndrome (RR:3.22; 95% CI:0.72 to 14.47; I(2)?=?73%) or acute kidney injury (RR: 11.52, 95% CI:0.03 to 4,159.80; I(2)?=?0%). The levels of hs-cTnI (MD:34.54 pg/ml;95% CI: 24.67 to 44.40 pg/ml; I(2)?=?88%), myoglobin (MD:186.81 ng/ml; 95% CI: 121.52 to 252.10 ng/ml; I(2)?=?88%), NT-pro BNP (MD:1183.55 pg/ml; 95% CI: 520.19 to 1846.91 pg/ml: I(2)?=?96%) and CK-MB (MD:2.49 ng/ml;95% CI: 1.86 to 3.12 ng/ml; I(2)?=?90%) were significantly elevated in nonsurvivors compared with survivors with COVID-19 infection. The results of this meta-analysis suggest that cardiac injury is associated with higher mortality, ICU admission, mechanical ventilation and coagulopathy in patients with COVID-19. Twit Text FOAVip Meta-analysis Comparing Outcomes in Patients With and Without Cardiac Injury and Coronavirus Disease 2019 (COVID 19) ????Am J Cardiol http://www.kidney.de/pget.php?&tw=1&pmid=33217345 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33217345 #FOAvip English Wikipedia <ref>{{Cite pmid|33217345}}</ref> Meta-analysis Comparing Outcomes in Patients With and Without Cardiac Injury and Coronavirus Disease 2019 (COVID 19) #MMPMID33217345 Bansal A; Kumar A; Patel D; Puri R; Kalra A; Kapadia SR; Reed GW Am J Cardiol 2021[Feb]; 141 (?): 140-146 PMID33217345show ga Current evidence is limited to small studies describing the association between cardiac injury and outcomes in patients with coronavirus disease 2019 (COVID-19). To address this, we performed a comprehensive meta-analysis of studies in COVID-19 patients to evaluate the association between cardiac injury and all-cause mortality, intensive care unit (ICU) admission, mechanical ventilation, acute respiratory distress syndrome, acute kidney injury and coagulopathy. Further, studies comparing cardiac biomarker levels in survivors versus nonsurvivors were included. A total of 14 studies (3,175 patients) were utilized for the final analysis. Cardiac injury in patients with COVID-19 was associated with higher risk of mortality (risk ratio [RR]:7.79; 95% confidence interval [CI]: 4.69 to 13.01; I(2)=58%), ICU admission (RR: 4.06; 95% CI: 1.50 to 10.97; I(2)?=?61%), mechanical ventilation (RR: 5.53; 95% CI: 3.09 to 9.91; I(2)?=?0%), and developing coagulopathy (RR: 3.86; 95% CI:2.81 to 5.32; I(2)?=?0%). However, cardiac injury was not associated with increased risk of acute respiratory distress syndrome (RR:3.22; 95% CI:0.72 to 14.47; I(2)?=?73%) or acute kidney injury (RR: 11.52, 95% CI:0.03 to 4,159.80; I(2)?=?0%). The levels of hs-cTnI (MD:34.54 pg/ml;95% CI: 24.67 to 44.40 pg/ml; I(2)?=?88%), myoglobin (MD:186.81 ng/ml; 95% CI: 121.52 to 252.10 ng/ml; I(2)?=?88%), NT-pro BNP (MD:1183.55 pg/ml; 95% CI: 520.19 to 1846.91 pg/ml: I(2)?=?96%) and CK-MB (MD:2.49 ng/ml;95% CI: 1.86 to 3.12 ng/ml; I(2)?=?90%) were significantly elevated in nonsurvivors compared with survivors with COVID-19 infection. The results of this meta-analysis suggest that cardiac injury is associated with higher mortality, ICU admission, mechanical ventilation and coagulopathy in patients with COVID-19. |*Pandemics[MESH] |COVID-19/*epidemiology[MESH] |Comorbidity[MESH] |Global Health[MESH] |Heart Diseases/*epidemiology[MESH] |Humans[MESH] |SARS-CoV-2[MESH]Meta-analysis Comparing Outcomes in Patients With and Without Cardiac (epmc).pdf DeepDyve Pubget Overpricing