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10.1172/JCI144807

http://scihub22266oqcxt.onion/10.1172/JCI144807
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33216734!7773392!33216734
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suck abstract from ncbi


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pmid33216734      J+Clin+Invest 2021 ; 131 (1): ä
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  • Does common cold coronavirus infection protect against severe SARS-CoV-2 disease? #MMPMID33216734
  • Meyerholz DK; Perlman S
  • J Clin Invest 2021[Jan]; 131 (1): ä PMID33216734show ga
  • The coronavirus disease 2019 (COVID-19) pandemic continues to cause morbidity and mortality. Since SARS coronavirus 2 (SARS-CoV-2) was identified as the cause for COVID-19, some have questioned whether exposure to seasonal common cold coronaviruses (CCCs) could provide tangible protection against SARS-CoV-2 infection or disease. In this issue of the JCI, Sagar et al. examined SARS-CoV-2 infections and outcomes of patients who had previously tested positive or negative for CCC infection (CCC+ or CCC-) by a comprehensive respiratory panel using PCR. No differences were seen between groups in terms of susceptibility to SARS-CoV-2 infection. However, hospitalized patients with a documented history of CCC infection had lower rates of intensive care unit (ICU) admissions and higher rates of survival than hospitalized CCC- patients. While these findings are associative and not causative, they highlight evidence suggesting that previous CCC infection may influence the disease course of SARS-CoV-2 infection.
  • |*COVID-19/epidemiology/immunology/prevention & control[MESH]
  • |*Pandemics[MESH]
  • |Common Cold/epidemiology/*immunology[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]


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