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10.1142/S0219720020500432 http://scihub22266oqcxt.onion/10.1142/S0219720020500432 33215965!ä!33215965 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Bioinform+Comput+Biol 2021 ; 19 (1): 2050043 Nephropedia Template TP {{tp|p=33215965|t=2021. An innovative method for the selection of inhibitors of the viral spike-glycoprotein of the SARS-CoV |pdf=|usr=}}{{33215965}} gab.com Text An innovative method for the selection of inhibitors of the viral spike-glycoprotein of the SARS-CoV JO: J Bioinform Comput Biol http://www.kidney.de/pget.php?&tw=1&pmid=33215965 #FOAvip This paper has developed and described a detailed method for selecting inhibitors based on modified natural peptides for the SARS-CoV BJ01 spike-glycoprotein. The selection of inhibitors is carried out by increasing the affinity of the peptide to the active center of the protein. This paper also provides a step-by-step algorithm for analyzing the affinity of protein interactions and presents an analysis of energy interactions between the active center of a protein and the wild-type peptide interacting with it, taking into account modifications of the latter. A description of the software package that implements the presented algorithm is given on the website https://binomlabs.com/covid19. Twit Text FOAVip An innovative method for the selection of inhibitors of the viral spike-glycoprotein of the SARS-CoV ????J Bioinform Comput Biol http://www.kidney.de/pget.php?&tw=1&pmid=33215965 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33215965 #FOAvip English Wikipedia <ref>{{Cite pmid|33215965}}</ref> An innovative method for the selection of inhibitors of the viral spike-glycoprotein of the SARS-CoV #MMPMID33215965 Koshlan TV; Kulikov KG J Bioinform Comput Biol 2021[Feb]; 19 (1): 2050043 PMID33215965show ga This paper has developed and described a detailed method for selecting inhibitors based on modified natural peptides for the SARS-CoV BJ01 spike-glycoprotein. The selection of inhibitors is carried out by increasing the affinity of the peptide to the active center of the protein. This paper also provides a step-by-step algorithm for analyzing the affinity of protein interactions and presents an analysis of energy interactions between the active center of a protein and the wild-type peptide interacting with it, taking into account modifications of the latter. A description of the software package that implements the presented algorithm is given on the website https://binomlabs.com/covid19. |Algorithms[MESH] |Amino Acid Substitution[MESH] |Antiviral Agents/*pharmacology[MESH] |Catalytic Domain[MESH] |Drug Evaluation, Preclinical/*methods[MESH] |Entropy[MESH] |Protein Interaction Domains and Motifs/genetics[MESH] |Proteins/chemistry/genetics/metabolism/pharmacology[MESH] |Software[MESH]An innovative method for the selection of inhibitors of the viral spi(epmc).pdf DeepDyve Pubget Overpricing