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10.1186/s41544-020-00056-z

http://scihub22266oqcxt.onion/10.1186/s41544-020-00056-z
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33209991!7548135!33209991
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suck abstract from ncbi


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pmid33209991      ExRNA 2020 ; 2 (1): 15
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  • RNA virus-encoded microRNAs: biogenesis, functions and perspectives on application #MMPMID33209991
  • Zhan S; Wang Y; Chen X
  • ExRNA 2020[]; 2 (1): 15 PMID33209991show ga
  • MicroRNAs (miRNAs) are small, noncoding RNAs that regulate gene expression at the posttranscriptional level and play a crucial role in development and many diseases. The discovery of miRNAs has greatly expanded our understanding of the intricate scenario of genome-wide regulation. Over the last two decades, hundreds of virus-encoded miRNAs have been identified, most of which are from DNA viruses. Although the number of reported RNA virus-derived miRNAs is increasing, current knowledge of their roles in physiological and pathological processes has remained lacking. In this review, we discuss the biogenesis and biological functions of RNA virus- encoded miRNAs and their proposed roles in virus-host interactions and further underscore their potential value in the diagnosis and treatment of viral diseases.
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