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10.1136/svn-2020-000652 http://scihub22266oqcxt.onion/10.1136/svn-2020-000652 33208493!7681795!33208493     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33208493&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Stroke+Vasc+Neurol 2020 ; 5 (4): 315-322 Nephropedia Template TP {{tp|p=33208493|t=2020. Cerebral microhaemorrhage in COVID-19: a critical illness related phenomenon?|pdf=|usr=}}{{33208493}} gab.com Text Cerebral microhaemorrhage in COVID-19: a critical illness related phenomenon JO: Stroke Vasc Neurol http://www.kidney.de/pget.php?&tw=1&pmid=33208493 #FOAvip BACKGROUND: Cerebral microhaemorrhages are increasingly being recognised as a complication of COVID-19. This observational retrospective study aims to further investigate the potential pathophysiology through assessing the pattern of microhaemorrhage and clinical characteristics of patients with COVID-19 and microhaemorrhage. By comparing with similar patterns of microhaemorrhage in other non-COVID-19 disease, this study aims to propose possible common pathogenic mechanisms. METHODS: A retrospective observational case series was performed identifying all patients with COVID-19 complicated by cerebral microhaemorrhage on MRI. The distribution and number of microhaemorrhages were recorded using the microbleed anatomical scale, and patients' baseline characteristics and salient test results were also recorded. RESULTS: Cerebral microhaemorrhages were noted to have a predilection for the corpus callosum, the juxtacortical white matter and brainstem. All patients had a preceding period of critical illness with respiratory failure and severe hypoxia necessitating intubation and mechanical ventilation. DISCUSSION: This study demonstrates a pattern of cerebral microhaemorrhage that is similar to the pattern reported in patients with non-COVID-19 related critical illness and other causes of severe hypoxia. This raises questions regarding whether microhaemorrhage occurs from endothelial dysfunction due the direct effect of SARS-CoV-2 infection or from the secondary effects of critical illness and hypoxia. Twit Text FOAVip Cerebral microhaemorrhage in COVID-19: a critical illness related phenomenon ????Stroke Vasc Neurol http://www.kidney.de/pget.php?&tw=1&pmid=33208493 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33208493 #FOAvip English Wikipedia <ref>{{Cite pmid|33208493}}</ref> Cerebral microhaemorrhage in COVID-19: a critical illness related phenomenon? #MMPMID33208493 Dixon L; McNamara C; Gaur P; Mallon D; Coughlan C; Tona F; Jan W; Wilson M; Jones B Stroke Vasc Neurol 2020[Dec]; 5 (4): 315-322 PMID33208493show ga BACKGROUND: Cerebral microhaemorrhages are increasingly being recognised as a complication of COVID-19. This observational retrospective study aims to further investigate the potential pathophysiology through assessing the pattern of microhaemorrhage and clinical characteristics of patients with COVID-19 and microhaemorrhage. By comparing with similar patterns of microhaemorrhage in other non-COVID-19 disease, this study aims to propose possible common pathogenic mechanisms. METHODS: A retrospective observational case series was performed identifying all patients with COVID-19 complicated by cerebral microhaemorrhage on MRI. The distribution and number of microhaemorrhages were recorded using the microbleed anatomical scale, and patients' baseline characteristics and salient test results were also recorded. RESULTS: Cerebral microhaemorrhages were noted to have a predilection for the corpus callosum, the juxtacortical white matter and brainstem. All patients had a preceding period of critical illness with respiratory failure and severe hypoxia necessitating intubation and mechanical ventilation. DISCUSSION: This study demonstrates a pattern of cerebral microhaemorrhage that is similar to the pattern reported in patients with non-COVID-19 related critical illness and other causes of severe hypoxia. This raises questions regarding whether microhaemorrhage occurs from endothelial dysfunction due the direct effect of SARS-CoV-2 infection or from the secondary effects of critical illness and hypoxia. |Aged[MESH] |Brain Stem/diagnostic imaging[MESH] |COVID-19/*complications/diagnostic imaging[MESH] |Cerebral Hemorrhage/diagnostic imaging/*etiology[MESH] |Corpus Callosum/diagnostic imaging[MESH] |Critical Illness[MESH] |Female[MESH] |Humans[MESH] |Magnetic Resonance Imaging[MESH] |Male[MESH] |Middle Aged[MESH] |Respiration, Artificial[MESH] |Respiratory Insufficiency/etiology[MESH] |Retrospective Studies[MESH] |Treatment Outcome[MESH]Cerebral microhaemorrhage in COVID-19: a critical illness related phen(epmc).pdf DeepDyve Pubget Overpricing