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10.1055/a-1300-2550

http://scihub22266oqcxt.onion/10.1055/a-1300-2550
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33207372!7781662!33207372
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suck abstract from ncbi

pmid33207372      Horm+Metab+Res 2021 ; 53 (1): 9-15
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  • The Role of Glucocorticoids in the Management of COVID-19 #MMPMID33207372
  • Alexaki VI; Henneicke H
  • Horm Metab Res 2021[Jan]; 53 (1): 9-15 PMID33207372show ga
  • Coronavirus disease 2019 (COVID-19), caused by an infection with the novel coronavirus SARS-CoV-2, has resulted in a global pandemic and poses an emergency to public health systems worldwide. COVID-19 is highly infectious and is characterized by an acute respiratory illness that varies from mild flu-like symptoms to the life-threatening acute respiratory distress syndrome (ARDS). As such, there is an urgent need for the development of new therapeutic strategies, which combat the high mortality in severely ill COVID-19 patients. Glucocorticoids are a frontline treatment for a diverse range of inflammatory diseases. Due to their immunosuppressive functions, the use of glucocorticoids in the treatment of COVID-19 patients was initially regarded with caution. However, recent studies concluded that the initiation of systemic glucocorticoids in patients suffering from severe and critical COVID-19 is associated with lower mortality. Herein we review the anti-inflammatory effects of glucocorticoids and discuss emerging issues in their clinical use in the context of COVID-19.
  • |*COVID-19 Drug Treatment[MESH]
  • |*SARS-CoV-2[MESH]
  • |Anti-Inflammatory Agents/*therapeutic use[MESH]
  • |Glucocorticoids/*therapeutic use[MESH]
  • |Humans[MESH]
  • |Immunosuppressive Agents/*therapeutic use[MESH]


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