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10.1093/infdis/jiaa724

http://scihub22266oqcxt.onion/10.1093/infdis/jiaa724
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33206973!7717347!33206973
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suck abstract from ncbi


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pmid33206973      J+Infect+Dis 2021 ; 223 (4): 562-567
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  • Monocyte CD169 Expression as a Biomarker in the Early Diagnosis of Coronavirus Disease 2019 #MMPMID33206973
  • Bedin AS; Makinson A; Picot MC; Mennechet F; Malergue F; Pisoni A; Nyiramigisha E; Montagnier L; Bollore K; Debiesse S; Morquin D; Veyrenche N; Renault C; Foulongne V; Bret C; Bourdin A; Le Moing V; Van de Perre P; Tuaillon E
  • J Infect Dis 2021[Feb]; 223 (4): 562-567 PMID33206973show ga
  • We assessed the expression of CD169, a type I interferon-inducible receptor, on monocytes (monocyte CD169 [mCD169]) in 53 adult patients admitted to the hospital during the coronavirus disease 2019 (COVID-19) outbreak for a suspicion of severe acute respiratory syndrome coronavirus 2 infection. Monocyte CD169 was strongly overexpressed in 30 of 32 (93.7%) confirmed COVID-19 cases, compared with 3 of 21 (14.3%) patients in whom the diagnosis of COVID-19 was finally ruled out. Monocyte CD169 was associated with the plasma interferon-alpha level and thrombocytopenia. Monocyte CD169 testing may be helpful for the rapid triage of suspected COVID-19 patients during an outbreak.
  • |Aged[MESH]
  • |Biomarkers/metabolism[MESH]
  • |COVID-19/*diagnosis/metabolism[MESH]
  • |Early Diagnosis[MESH]
  • |Female[MESH]
  • |Flow Cytometry[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Monocytes/*metabolism/virology[MESH]
  • |ROC Curve[MESH]


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