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10.14348/molcells.2020.0177 http://scihub22266oqcxt.onion/10.14348/molcells.2020.0177 33199671!7700842!33199671     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Mol+Cells 2020 ; 43 (11): 953-963 Nephropedia Template TP {{tp|p=33199671|t=2020. Expression Analyses of MicroRNAs in Hamster Lung Tissues Infected by SARS-CoV-2 |pdf=|usr=}}{{33199671}} gab.com Text Expression Analyses of MicroRNAs in Hamster Lung Tissues Infected by SARS-CoV-2 JO: Mol Cells http://www.kidney.de/pget.php?&tw=1&pmid=33199671 #FOAvip Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is an infectious disease with multiple severe symptoms, such as fever over 37.5 degrees C, cough, dyspnea, and pneumonia. In our research, microRNAs (miRNAs) binding to the genome sequences of severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory-related coronavirus (MERS-CoV), and SARS-CoV-2 were identified by bioinformatic tools. Five miRNAs (hsa-miR-15a-5p, hsa-miR-15b-5p, hsa-miR-195-5p, hsa-miR-16-5p, and hsa-miR-196a-1-3p) were found to commonly bind to SARS-CoV, MERS-CoV, and SARS-CoV-2. We also identified miRNAs that bind to receptor proteins, such as ACE2, ADAM17, and TMPRSS2, which are important for understanding the infection mechanism of SARS-CoV-2. The expression patterns of those miRNAs were examined in hamster lung samples infected by SARS-CoV-2. Five miRNAs (hsa-miR-15b-5p, hsa-miR-195-5p, hsa-miR-221-3p, hsa-miR-140-3p, and hsa-miR-422a) showed differential expression patterns in lung tissues before and after infection. Especially, hsa-miR-15b-5p and hsa-miR-195-5p showed a large difference in expression, indicating that they may potentially be diagnostic biomarkers for SARS-CoV-2 infection. Twit Text FOAVip Expression Analyses of MicroRNAs in Hamster Lung Tissues Infected by SARS-CoV-2 ????Mol Cells http://www.kidney.de/pget.php?&tw=1&pmid=33199671 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33199671 #FOAvip English Wikipedia <ref>{{Cite pmid|33199671}}</ref> Expression Analyses of MicroRNAs in Hamster Lung Tissues Infected by SARS-CoV-2 #MMPMID33199671 Kim WR; Park EG; Kang KW; Lee SM; Kim B; Kim HS Mol Cells 2020[Nov]; 43 (11): 953-963 PMID33199671show ga Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is an infectious disease with multiple severe symptoms, such as fever over 37.5 degrees C, cough, dyspnea, and pneumonia. In our research, microRNAs (miRNAs) binding to the genome sequences of severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory-related coronavirus (MERS-CoV), and SARS-CoV-2 were identified by bioinformatic tools. Five miRNAs (hsa-miR-15a-5p, hsa-miR-15b-5p, hsa-miR-195-5p, hsa-miR-16-5p, and hsa-miR-196a-1-3p) were found to commonly bind to SARS-CoV, MERS-CoV, and SARS-CoV-2. We also identified miRNAs that bind to receptor proteins, such as ACE2, ADAM17, and TMPRSS2, which are important for understanding the infection mechanism of SARS-CoV-2. The expression patterns of those miRNAs were examined in hamster lung samples infected by SARS-CoV-2. Five miRNAs (hsa-miR-15b-5p, hsa-miR-195-5p, hsa-miR-221-3p, hsa-miR-140-3p, and hsa-miR-422a) showed differential expression patterns in lung tissues before and after infection. Especially, hsa-miR-15b-5p and hsa-miR-195-5p showed a large difference in expression, indicating that they may potentially be diagnostic biomarkers for SARS-CoV-2 infection. |ADAM17 Protein/genetics/metabolism[MESH] |Angiotensin-Converting Enzyme 2/genetics/metabolism[MESH] |Animals[MESH] |COVID-19/*genetics[MESH] |Cells, Cultured[MESH] |Computational Biology[MESH] |Cricetinae[MESH] |Gene Expression Regulation[MESH] |Genetic Markers/genetics[MESH] |Humans[MESH] |Lung/physiology/*virology[MESH] |MicroRNAs/genetics[MESH] |Middle East Respiratory Syndrome Coronavirus/*physiology[MESH] |Pandemics[MESH] |SARS-CoV-2/*physiology[MESH] |Serine Endopeptidases/genetics/metabolism[MESH]Expression Analyses of MicroRNAs in Hamster Lung Tissues Infected by S(epmc).pdf DeepDyve Pubget Overpricing