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10.1007/s12192-020-01180-3 http://scihub22266oqcxt.onion/10.1007/s12192-020-01180-3 33196989!7667470!33196989     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cell+Stress+Chaperones 2021 ; 26 (1): 1-2 Nephropedia Template TP {{tp|p=33196989|t=2021. Covid-19, heat shock proteins, and autoimmune bullous diseases: a potential link deserving further attention |pdf=|usr=}}{{33196989}} gab.com Text Covid-19, heat shock proteins, and autoimmune bullous diseases: a potential link deserving further attention JO: Cell Stress Chaperones http://www.kidney.de/pget.php?&tw=1&pmid=33196989 #FOAvip A link between Covid-19 and development of autoimmunity has been reported. A possible explanation could be molecular mimicry between SARS-CoV-2 and human proteins. Peptide sharing has been found between antigenic epitopes of this virus and heat shock proteins (Hsp) 60 and 90, both of which are associated with autoimmune diseases including those of the bullous type. In particular, there is evidence for the latter Hsp acting as a pathophysiological factor and treatment target in autoimmune blistering dermatoses. Considering multimodal anti-inflammatory mechanisms of action of anti-Hsp90 treatment and drug repositioning results, it may be hypothesized that Hsp90 inhibition could also be a treatment option for cytokine storm-mediated acute respiratory distress syndrome in Covid-19 patients. Hence, although Covid-19-induced autoimmune bullous diseases have not been described in the literature so far, the potential relationship between Covid-19, Hsp, and these autoimmune disorders deserves further attention with respect to both pathophysiology and treatment. Twit Text FOAVip Covid-19, heat shock proteins, and autoimmune bullous diseases: a potential link deserving further attention ????Cell Stress Chaperones http://www.kidney.de/pget.php?&tw=1&pmid=33196989 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33196989 #FOAvip English Wikipedia <ref>{{Cite pmid|33196989}}</ref> Covid-19, heat shock proteins, and autoimmune bullous diseases: a potential link deserving further attention #MMPMID33196989 Kasperkiewicz M Cell Stress Chaperones 2021[Jan]; 26 (1): 1-2 PMID33196989show ga A link between Covid-19 and development of autoimmunity has been reported. A possible explanation could be molecular mimicry between SARS-CoV-2 and human proteins. Peptide sharing has been found between antigenic epitopes of this virus and heat shock proteins (Hsp) 60 and 90, both of which are associated with autoimmune diseases including those of the bullous type. In particular, there is evidence for the latter Hsp acting as a pathophysiological factor and treatment target in autoimmune blistering dermatoses. Considering multimodal anti-inflammatory mechanisms of action of anti-Hsp90 treatment and drug repositioning results, it may be hypothesized that Hsp90 inhibition could also be a treatment option for cytokine storm-mediated acute respiratory distress syndrome in Covid-19 patients. Hence, although Covid-19-induced autoimmune bullous diseases have not been described in the literature so far, the potential relationship between Covid-19, Hsp, and these autoimmune disorders deserves further attention with respect to both pathophysiology and treatment. |*Autoimmune Diseases[MESH] |*COVID-19[MESH] |*Guillain-Barre Syndrome[MESH] |Attention[MESH] |Heat-Shock Proteins[MESH] |Humans[MESH] |Molecular Mimicry[MESH]Covid-19, heat shock proteins, and autoimmune bullous diseases: a pote(epmc).pdf DeepDyve Pubget Overpricing