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Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Intern+Med+J 2021 ; 51 (1): 42-51 Nephropedia Template TP
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COVID-19 in Australia: our national response to the first cases of SARS-CoV-2 infection during the early biocontainment phase #MMPMID33196128
Shaban RZ; Li C; O'Sullivan MVN; Gerrard J; Stuart RL; Teh J; Gilroy N; Sorrell TC; White E; Bag S; Hackett K; Chen SCA; Kok J; Dwyer DE; Iredell JR; Maddocks S; Ferguson P; Varshney K; Carter I; Barratt R; Robertson M; Baskar SR; Friend C; Robosa RS; Sotomayor-Castillo C; Nahidi S; Macbeth DA; Alcorn KAD; Wattiaux A; Moore F; McMahon J; Naughton W; Korman TM; Catton M; Kanapathipillai R; Romanes F; Rowe E; Catford J; Kennedy B; Qiao M; Shaw D
Intern Med J 2021[Jan]; 51 (1): 42-51 PMID33196128show ga
BACKGROUND: On 31 December 2019, the World Health Organization recognised clusters of pneumonia-like cases due to a novel coronavirus disease (COVID-19). COVID-19 became a pandemic 71 days later. AIM: To report the clinical and epidemiological features, laboratory data and outcomes of the first group of 11 returned travellers with COVID-19 in Australia. METHODS: This is a retrospective, multi-centre case series. All patients with confirmed COVID-19 infection were admitted to tertiary referral hospitals in New South Wales, Queensland, Victoria and South Australia. RESULTS: The median age of the patient cohort was 42 years (interquartile range (IQR), 24-53 years) with six men and five women. Eight (72.7%) patients had returned from Wuhan, one from Shenzhen, one from Japan and one from Europe. Possible human-to-human transmission from close family contacts in gatherings overseas occurred in two cases. Symptoms on admission were fever, cough and sore throat (n = 9, 81.8%). Co-morbidities included hypertension (n = 3, 27.3%) and hypercholesterolaemia (n = 2, 18.2%). No patients developed severe acute respiratory distress nor required intensive care unit admission or mechanical ventilation. After a median hospital stay of 14.5 days (IQR, 6.75-21), all patients were discharged. CONCLUSIONS: This is a historical record of the first COVID-19 cases in Australia during the early biocontainment phase of the national response. These findings were invaluable for establishing early inpatient and outpatient COVID-19 models of care and informing the management of COVID-19 over time as the outbreak evolved. Future research should extend this Australian case series to examine global epidemiological variation of this novel infection.