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10.1016/j.patter.2020.100155

http://scihub22266oqcxt.onion/10.1016/j.patter.2020.100155
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33196056!7649624!33196056
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suck abstract from ncbi


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pmid33196056      Patterns+(N+Y) 2021 ; 2 (1): 100155
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  • KG-COVID-19: A Framework to Produce Customized Knowledge Graphs for COVID-19 Response #MMPMID33196056
  • Reese JT; Unni D; Callahan TJ; Cappelletti L; Ravanmehr V; Carbon S; Shefchek KA; Good BM; Balhoff JP; Fontana T; Blau H; Matentzoglu N; Harris NL; Munoz-Torres MC; Haendel MA; Robinson PN; Joachimiak MP; Mungall CJ
  • Patterns (N Y) 2021[Jan]; 2 (1): 100155 PMID33196056show ga
  • Integrated, up-to-date data about SARS-CoV-2 and COVID-19 is crucial for the ongoing response to the COVID-19 pandemic by the biomedical research community. While rich biological knowledge exists for SARS-CoV-2 and related viruses (SARS-CoV, MERS-CoV), integrating this knowledge is difficult and time-consuming, since much of it is in siloed databases or in textual format. Furthermore, the data required by the research community vary drastically for different tasks; the optimal data for a machine learning task, for example, is much different from the data used to populate a browsable user interface for clinicians. To address these challenges, we created KG-COVID-19, a flexible framework that ingests and integrates heterogeneous biomedical data to produce knowledge graphs (KGs), and applied it to create a KG for COVID-19 response. This KG framework also can be applied to other problems in which siloed biomedical data must be quickly integrated for different research applications, including future pandemics.
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