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10.3389/fmolb.2020.00204

http://scihub22266oqcxt.onion/10.3389/fmolb.2020.00204
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33195397!7477106!33195397
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suck abstract from ncbi

pmid33195397      Front+Mol+Biosci 2020 ; 7 (?): 204
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  • Drug Weaponry to Fight Against SARS-CoV-2 #MMPMID33195397
  • Cabezon E; Arechaga I
  • Front Mol Biosci 2020[]; 7 (?): 204 PMID33195397show ga
  • The current outbreak of SARS-CoV-2 virus has caused a large increase in mortality and morbidity associated with respiratory diseases. Huge efforts are currently ongoing to develop a vaccine against this virus. However, alternative approaches could be considered in the fight against this disease. Among other strategies, structural-based drug design could be an effective approach to generate specific molecules against SARS-CoV-2, thus reducing viral burden in infected patients. Here, in addition to this structural approach, we also revise several therapeutic strategies to fight against this viral threat. Furthermore, we report ACE-2 genetic polymorphic variants affecting residues involved in close contacts with SARS-CoV-2 that might be associated to different infection risks. These analyses could provide valuable information to predict the course of the disease.
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