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10.3389/fmicb.2020.567317 http://scihub22266oqcxt.onion/10.3389/fmicb.2020.567317 33193156!7644843!33193156     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Microbiol 2020 ; 11 (ä): 567317 Nephropedia Template TP {{tp|p=33193156|t=2020. G-Quadruplexes Are Present in Human Coronaviruses Including SARS-CoV-2 |pdf=|usr=}}{{33193156}} gab.com Text G-Quadruplexes Are Present in Human Coronaviruses Including SARS-CoV-2 JO: Front Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=33193156 #FOAvip The global coronavirus disease 2019 (COVID-19) pandemic is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is one of seven human coronaviruses. G-quadruplexes are intrinsic obstacles to genome replication. Whether G-quadruplexes are present in human coronaviruses is unknown. In the current study, we have predicted that all seven human coronaviruses harbor G-quadruplex sequences. Conserved G-quadruplex sequences in SARS-CoV and SARS-CoV-2 were analyzed and verified by circular dichroism (CD) spectroscopy and Thioflavin T fluorescence assay. Similar to SARS-CoV, SARS-CoV-2 encodes an nsP3 protein, which is predicted to associate with G-quadruplexes. Targeting G-quadruplex sequences in the SARS-CoV-2 genome by G-quadruplex ligands could be a new way to conquer COVID-19. Twit Text FOAVip G-Quadruplexes Are Present in Human Coronaviruses Including SARS-CoV-2 ????Front Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=33193156 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33193156 #FOAvip English Wikipedia <ref>{{Cite pmid|33193156}}</ref> G-Quadruplexes Are Present in Human Coronaviruses Including SARS-CoV-2 #MMPMID33193156 Cui H; Zhang L Front Microbiol 2020[]; 11 (ä): 567317 PMID33193156show ga The global coronavirus disease 2019 (COVID-19) pandemic is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is one of seven human coronaviruses. G-quadruplexes are intrinsic obstacles to genome replication. Whether G-quadruplexes are present in human coronaviruses is unknown. In the current study, we have predicted that all seven human coronaviruses harbor G-quadruplex sequences. Conserved G-quadruplex sequences in SARS-CoV and SARS-CoV-2 were analyzed and verified by circular dichroism (CD) spectroscopy and Thioflavin T fluorescence assay. Similar to SARS-CoV, SARS-CoV-2 encodes an nsP3 protein, which is predicted to associate with G-quadruplexes. Targeting G-quadruplex sequences in the SARS-CoV-2 genome by G-quadruplex ligands could be a new way to conquer COVID-19. äG-Quadruplexes Are Present in Human Coronaviruses Including SARS-CoV-2(epmc).pdf DeepDyve Pubget Overpricing