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10.5414/CP203817

http://scihub22266oqcxt.onion/10.5414/CP203817
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33191908!ä!33191908

suck abstract from ncbi


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pmid33191908      Int+J+Clin+Pharmacol+Ther 2021 ; 59 (3): 175-181
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  • Drug therapy strategies for COVID-19 infection during pregnancy #MMPMID33191908
  • Wang H; Gao Y; Wu B
  • Int J Clin Pharmacol Ther 2021[Mar]; 59 (3): 175-181 PMID33191908show ga
  • Acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) has spread rapidly in numerous countries and caused a massive number of deaths. Interferon-alpha (IFN-alpha), lopinavir/ritonavir, chloroquine phosphate, arbidol, ribavirin, remdesivir, and dexamethasone are the therapeutic drugs recommended for treating 2019-nCoV disease (COVID-19 disease). Due to the particularity of immune function, pregnant women seem to be more susceptible to the virus. We searched the literature to find effective and safe drugs for patients with COVID-19 during pregnancy and to provide drug therapy strategies for medical staff. According to the current literature we reviewed, we suggest that IFN-alpha and arbidol can be retained in the treatment regimen for pregnant women and that to reduce maternal mortality, appropriate doses of dexamethasone can be given to those who are predicted to have low premature survival and to receive mechanical ventilation or oxygen. However, the use of dexamethasone in the 1(st) trimester and after 37 weeks of gestation should be avoided.
  • |*COVID-19[MESH]
  • |*Coronavirus Infections/drug therapy[MESH]
  • |*Pregnancy Complications, Infectious/drug therapy[MESH]
  • |Antiviral Agents/adverse effects[MESH]
  • |Drug Combinations[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Pregnancy[MESH]


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