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10.1016/j.ajem.2020.10.068

http://scihub22266oqcxt.onion/10.1016/j.ajem.2020.10.068
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33189516!7642742!33189516
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suck abstract from ncbi


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pmid33189516      Am+J+Emerg+Med 2021 ; 46 (ä): 489-494
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  • Identifying patients with symptoms suspicious for COVID-19 at elevated risk of adverse events: The COVAS score #MMPMID33189516
  • Sharp AL; Huang BZ; Broder B; Smith M; Yuen G; Subject C; Nau C; Creekmur B; Tartof S; Gould MK
  • Am J Emerg Med 2021[Aug]; 46 (ä): 489-494 PMID33189516show ga
  • OBJECTIVE: Develop and validate a risk score using variables available during an Emergency Department (ED) encounter to predict adverse events among patients with suspected COVID-19. METHODS: A retrospective cohort study of adult visits for suspected COVID-19 between March 1 - April 30, 2020 at 15 EDs in Southern California. The primary outcomes were death or respiratory decompensation within 7-days. We used least absolute shrinkage and selection operator (LASSO) models and logistic regression to derive a risk score. We report metrics for derivation and validation cohorts, and subgroups with pneumonia or COVID-19 diagnoses. RESULTS: 26,600 ED encounters were included and 1079 experienced an adverse event. Five categories (comorbidities, obesity/BMI >/= 40, vital signs, age and sex) were included in the final score. The area under the curve (AUC) in the derivation cohort was 0.891 (95% CI, 0.880-0.901); similar performance was observed in the validation cohort (AUC = 0.895, 95% CI, 0.874-0.916). Sensitivity ranging from 100% (Score 0) to 41.7% (Score of >/=15) and specificity from 13.9% (score 0) to 96.8% (score >/= 15). In the subgroups with pneumonia (n = 3252) the AUCs were 0.780 (derivation, 95% CI 0.759-0.801) and 0.832 (validation, 95% CI 0.794-0.870), while for COVID-19 diagnoses (n = 2059) the AUCs were 0.867 (95% CI 0.843-0.892) and 0.837 (95% CI 0.774-0.899) respectively. CONCLUSION: Physicians evaluating ED patients with pneumonia, COVID-19, or symptoms suspicious for COVID-19 can apply the COVAS score to assist with decisions to hospitalize or discharge patients during the SARS CoV-2 pandemic.
  • |*Pandemics[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |COVID-19/diagnosis/*epidemiology[MESH]
  • |Emergency Service, Hospital/*statistics & numerical data[MESH]
  • |Female[MESH]
  • |Follow-Up Studies[MESH]
  • |Hospitalization/*statistics & numerical data[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Retrospective Studies[MESH]
  • |Risk Assessment/*methods[MESH]
  • |Risk Factors[MESH]
  • |SARS-CoV-2[MESH]


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