Prevalence of obesity and hypovitaminosis D in elderly with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) #MMPMID33183522
Goncalves TJM; Goncalves SEAB; Guarnieri A; Risegato RC; Guimaraes MP; de Freitas DC; Razuk-Filho A; Benedito Junior PB; Parrillo EF
Clin Nutr ESPEN 2020[Dec]; 40 (?): 110-114 PMID33183522show ga
BACKGROUND & AIM: Verify the prevalence of hypovitaminosis D and obesity in elderly patients infected by new coronavirus. The patients developed severe symptoms and were admitted in intensive care unit (ICU) to receive invasive ventilation due to diagnosis of acute respiratory distress syndrome (ARDS). METHODS: A cross-sectional descriptive study composed of elderly (age >/= 60 years) admitted to the ICU. Were collected demographic (sex, age), anthropometric data, presence of comorbidities (hypertension, diabetes, heart disease, lung, neurological and oncological diseases), severity score in ICU (SAPS III), PaO(2)/FiO(2) ratio, analysis of C-reactive protein (CRP) and serum dosage of 25-hydroxy vitamin D (25 OHD) in the first day of hospitalization to identify elderly with hypovitaminosis D (low values < 30 ng/mL). The diagnosis of obesity in elderly was determined by calculating the body mass index (BMI) >/= 30 kg/m(2). RESULTS: A total of 176 elderly met the inclusion criteria. 54% were elderly men and mean age of 72.9 +/- 9.1 years. The median BMI was 30.5 (28.1-33) kg/m(2) with 68.7% having a nutritional diagnosis of obesity and 15.3% had BMI >/= 35 kg/m(2). The most prevalent comorbidities were hypertension (72.2%) and diabetes (40.9%). Prevalence of hypovitaminosis D with values of 25 OHD <30 ng/mL, < 20 ng/mL and <10 ng/mL was 93.8%, 65.9% and 21% respectively. The prevalence of hypovitaminosis D (<30 ng/mL) in obese elderly was 94.2%. There was a negative and significant bivariate correlation between BMI and levels of 25 OHD (r = - 0.15; p = 0.04). CONCLUSION: Hypovitaminosis D and obesity in elderly have a high prevalence in critically ill patients in ICU infected by the new coronavirus. Laboratory investigation of vitamin D becomes important, especially in obese elderly patients.
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Clin+Nutr+ESPEN 2020 ; 40 (?): 110-114
