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10.3390/nu12113441 http://scihub22266oqcxt.onion/10.3390/nu12113441 33182607!7697804!33182607     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 284.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nutrients 2020 ; 12 (11): ä Nephropedia Template TP {{tp|p=33182607|t=2020. A Probiotic Lactobacillus gasseri Alleviates Escherichia coli-Induced Cognitive Impairment and Depression in Mice by Regulating IL-1beta Expression and Gut Microbiota |pdf=|usr=}}{{33182607}} gab.com Text A Probiotic Lactobacillus gasseri Alleviates Escherichia coli-Induced Cognitive Impairment and Depression in Mice by Regulating IL-1beta Expression and Gut Microbiota JO: Nutrients http://www.kidney.de/pget.php?&tw=1&pmid=33182607 #FOAvip Excessive expression of interleukin (IL)-1beta in the brain causes depression and cognitive dysfunction. Herein, we investigated the effect of Lactobacillus gasseri NK109, which suppressed IL-1beta expression in activated macrophages, on Escherichia coli K1-induced cognitive impairment and depression in mice. Germ-free and specific pathogen-free mice with neuropsychiatric disorders were prepared by oral gavage of K1. NK109 alleviated K1-induced cognition-impaired and depressive behaviors, decreased the expression of IL-1beta and populations of NF-kappaB(+)/Iba1(+) and IL-1R(+) cells, and increased the K1-suppressed population of BDNF(+)/NeuN(+) cells in the hippocampus. However, its effects were partially attenuated by celiac vagotomy. NK109 treatment mitigated K1-induced colitis and gut dysbiosis. Tyndallized NK109, even if lysed, alleviated cognitive impairment and depression. In conclusion, NK109 alleviated neuropsychiatric disorders and colitis by modulating IL-1beta expression, gut microbiota, and vagus nerve-mediated gut-brain signaling. Twit Text FOAVip A Probiotic Lactobacillus gasseri Alleviates Escherichia coli-Induced Cognitive Impairment and Depression in Mice by Regulating IL-1beta Expression and Gut Microbiota ????Nutrients http://www.kidney.de/pget.php?&tw=1&pmid=33182607 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33182607 #FOAvip English Wikipedia <ref>{{Cite pmid|33182607}}</ref> A Probiotic Lactobacillus gasseri Alleviates Escherichia coli-Induced Cognitive Impairment and Depression in Mice by Regulating IL-1beta Expression and Gut Microbiota #MMPMID33182607 Yun SW; Kim JK; Lee KE; Oh YJ; Choi HJ; Han MJ; Kim DH Nutrients 2020[Nov]; 12 (11): ä PMID33182607show ga Excessive expression of interleukin (IL)-1beta in the brain causes depression and cognitive dysfunction. Herein, we investigated the effect of Lactobacillus gasseri NK109, which suppressed IL-1beta expression in activated macrophages, on Escherichia coli K1-induced cognitive impairment and depression in mice. Germ-free and specific pathogen-free mice with neuropsychiatric disorders were prepared by oral gavage of K1. NK109 alleviated K1-induced cognition-impaired and depressive behaviors, decreased the expression of IL-1beta and populations of NF-kappaB(+)/Iba1(+) and IL-1R(+) cells, and increased the K1-suppressed population of BDNF(+)/NeuN(+) cells in the hippocampus. However, its effects were partially attenuated by celiac vagotomy. NK109 treatment mitigated K1-induced colitis and gut dysbiosis. Tyndallized NK109, even if lysed, alleviated cognitive impairment and depression. In conclusion, NK109 alleviated neuropsychiatric disorders and colitis by modulating IL-1beta expression, gut microbiota, and vagus nerve-mediated gut-brain signaling. |Animals[MESH] |Behavior, Animal[MESH] |Cognitive Dysfunction[MESH] |Colitis/psychology/*therapy[MESH] |Depression[MESH] |Dysbiosis/psychology/therapy[MESH] |Escherichia coli/immunology/*physiology[MESH] |Feces/microbiology[MESH] |Gastrointestinal Microbiome/immunology/*physiology[MESH] |Hippocampus/drug effects/metabolism[MESH] |Interleukin-1beta/*metabolism[MESH] |Lactobacillus gasseri/immunology/*physiology[MESH] |Lipopolysaccharides[MESH] |Male[MESH] |Mice[MESH] |Mice, Inbred C57BL[MESH] |Microbial Interactions/*physiology[MESH] |NF-kappa B/metabolism[MESH]A Probiotic Lactobacillus gasseri Alleviates Escherichia coli-Induced (epmc).pdf DeepDyve Pubget Overpricing