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10.1016/j.kint.2020.10.032 http://scihub22266oqcxt.onion/10.1016/j.kint.2020.10.032 33181156!7833801!33181156     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Kidney+Int 2021 ; 99 (1): 227-237 Nephropedia Template TP {{tp|p=33181156|t=2021. Results from the IRoc-GN international registry of patients with COVID-19 and glomerular disease suggest close monitoring |pdf=|usr=}}{{33181156}} gab.com Text Results from the IRoc-GN international registry of patients with COVID-19 and glomerular disease suggest close monitoring JO: Kidney Int http://www.kidney.de/pget.php?&tw=1&pmid=33181156 #FOAvip The effects of SARS-CoV-2 infection on individuals with immune-mediated glomerulonephritis, who are often undergoing immunosuppressive treatments, are unknown. Therefore, we created the International Registry of COVID infection in glomerulonephritis (IRoc-GN) and identified 40 patients with glomerulonephritis and COVID-19 followed in centers in North America and Europe. Detailed information on glomerulonephritis diagnosis, kidney parameters, and baseline immunosuppression prior to infection were recorded, as well as clinical presentation, laboratory values, treatment, complications, and outcomes of COVID-19. This cohort was compared to 80 COVID-positive control cases from the general population without glomerulonephritis matched for the time of infection. The majority (70%) of the patients with glomerulonephritis and all the controls were hospitalized. Patients with glomerulonephritis had significantly higher mortality (15% vs. 5%, respectively) and acute kidney injury (39% vs. 14%) than controls, while the need for kidney replacement therapy was not statistically different between the two groups. Receiving immunosuppression or renin-angiotensin-aldosterone system inhibitors at presentation did not increase the risk of death or acute kidney injury in the glomerulonephritis cohort. In the cohort with glomerulonephritis, lower serum albumin at presentation and shorter duration of glomerular disease were associated with greater risk of acute kidney injury and need for kidney replacement therapy. No differences in outcomes occurred between patients with primary glomerulonephritis versus glomerulonephritis associated with a systemic autoimmune disease (lupus or vasculitis). Thus, due to the higher mortality and risk of acute kidney injury than in the general population without glomerulonephritis, patients with glomerulonephritis and COVID-19 should be carefully monitored, especially when they present with low serum albumin levels. Twit Text FOAVip Results from the IRoc-GN international registry of patients with COVID-19 and glomerular disease suggest close monitoring ????Kidney Int http://www.kidney.de/pget.php?&tw=1&pmid=33181156 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33181156 #FOAvip English Wikipedia <ref>{{Cite pmid|33181156}}</ref> Results from the IRoc-GN international registry of patients with COVID-19 and glomerular disease suggest close monitoring #MMPMID33181156 Waldman M; Soler MJ; Garcia-Carro C; Lightstone L; Turner-Stokes T; Griffith M; Torras J; Valenzuela LM; Bestard O; Geddes C; Flossmann O; Budge KL; Cantarelli C; Fiaccadori E; Delsante M; Morales E; Gutierrez E; Nino-Cruz JA; Martinez-Rueda AJ; Comai G; Bini C; La Manna G; Slon MF; Manrique J; Agraz I; Sinaii N; Cravedi P Kidney Int 2021[Jan]; 99 (1): 227-237 PMID33181156show ga The effects of SARS-CoV-2 infection on individuals with immune-mediated glomerulonephritis, who are often undergoing immunosuppressive treatments, are unknown. Therefore, we created the International Registry of COVID infection in glomerulonephritis (IRoc-GN) and identified 40 patients with glomerulonephritis and COVID-19 followed in centers in North America and Europe. Detailed information on glomerulonephritis diagnosis, kidney parameters, and baseline immunosuppression prior to infection were recorded, as well as clinical presentation, laboratory values, treatment, complications, and outcomes of COVID-19. This cohort was compared to 80 COVID-positive control cases from the general population without glomerulonephritis matched for the time of infection. The majority (70%) of the patients with glomerulonephritis and all the controls were hospitalized. Patients with glomerulonephritis had significantly higher mortality (15% vs. 5%, respectively) and acute kidney injury (39% vs. 14%) than controls, while the need for kidney replacement therapy was not statistically different between the two groups. Receiving immunosuppression or renin-angiotensin-aldosterone system inhibitors at presentation did not increase the risk of death or acute kidney injury in the glomerulonephritis cohort. In the cohort with glomerulonephritis, lower serum albumin at presentation and shorter duration of glomerular disease were associated with greater risk of acute kidney injury and need for kidney replacement therapy. No differences in outcomes occurred between patients with primary glomerulonephritis versus glomerulonephritis associated with a systemic autoimmune disease (lupus or vasculitis). Thus, due to the higher mortality and risk of acute kidney injury than in the general population without glomerulonephritis, patients with glomerulonephritis and COVID-19 should be carefully monitored, especially when they present with low serum albumin levels. |Acute Kidney Injury/*epidemiology/etiology[MESH] |Adult[MESH] |Aged[MESH] |Aged, 80 and over[MESH] |Angiotensin-Converting Enzyme Inhibitors/*adverse effects[MESH] |COVID-19/complications/*immunology/mortality/virology[MESH] |Europe/epidemiology[MESH] |Female[MESH] |Glomerulonephritis/complications/drug therapy/*immunology/mortality[MESH] |Humans[MESH] |Immunosuppressive Agents/*adverse effects[MESH] |International Cooperation[MESH] |Male[MESH] |Middle Aged[MESH] |North America/epidemiology[MESH] |Registries/statistics & numerical data[MESH] |Retrospective Studies[MESH]Results from the IRoc-GN international registry of patients with COVID(epmc).pdf DeepDyve Pubget Overpricing